Cardiovascular Flashcards

1
Q

Mycetismus sanguinari cause

A

helvella
(it resembles an edible morchella)

(mushroom)

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2
Q

mycetismus sanguinarius ss

A

hemoglobinuria
hemolysis
jaundice 6-8 h after ingestion-> death

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3
Q

subQ zygomycosis caused by?

A

besidiobolus ranarum: basidiobolomycosis
delacroixia coronets: conidiobolomycosis

(mold)

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4
Q

subQ zygomycosis (basidiomycosis and conidiomycosis)
location
reservoir
path

A

basidiobolus ranarum : Africa and Asia soil
reservoid- reptile dung and decay veggies
pathogen- reptilians and amphibians

delacroixia coronatus: Central America Africa India
reservoir- soil
pathogen- insects

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5
Q

basidiomycosis and conidiomycosis transmisison

A

traumatic implantation

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6
Q

basidiomycosis and conidiomycosis
immunity
path

A

no immunity

invited and cause granulomas

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7
Q

basidiomycosis

ss

A

freely movable sub q nodules that are hyper pigmented

associated with lymphatics- causing elephantiasis -

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8
Q

conidiomycosis

ss

A

nasal swellings that turn into nasal polyps

causing edema of cheeks forehead lips and eyes

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9
Q

basidiomycosis and conidiomycosis

dx

A

basidiomycosis- septate with swollen ends and large papilla

conidiomycosis- hyphae w terminal conidia

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10
Q

basidiomycosis and conidiomycosis

tx

A

ketoconazole

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11
Q

Sporotrichosis

cause

A

sporthrix schenkii

dimorphic mold

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12
Q

Sporotrichosis

epi

A

worldwide - in decay veg and soil

transmission- traumatic implantation

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13
Q

Sporotrichosis

path

A

invade lymphatics- causing circumscribed microabcesses

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14
Q

Sporotrichosis

ss

A

painless nodular necrotic lesions
Follow lymphatic tract from primary lesion
fixed- single ulcer
mucocutaneous- ulcer
pulmonary- lung lesions/ bronchial obstruction

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15
Q

Sporotrichosis

dx

A

clamydospores in asteroid bodies**

and sugar shaped budding yeast

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16
Q

Sporotrichosis

tx

A

itraconazole

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17
Q

rhodotulosis caused by?

A

candida
rhodotorula
sarachomyces
schizosaraco

(monomorphic oppotunistic yeasts)

(mainly seen as a hospital infection-

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18
Q

rhodotulosis
epi
transmission

A

worldwide
common contaminants of skin lungs etc
transmitted person to person with contaminated needles, cath or equipment

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19
Q

rhodotulosis

path

A

enter blood and cause fungemia
release compounds that cause pyrogens- due to fermentation byproducts

(after surgery more common infections of these)

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20
Q

rhodotulosis

ss

A

fever hypotension tacky
endocarditis chills
shock if fungemia

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21
Q

rhodotulosis

dx

A

individual spherical budding non encapsulated yeast cells

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22
Q

rhodotulosis

tx

A

removal of source of contamination

23
Q

babesiosis

caused by

A

babesia divergens
babesia microti

(protozoan)

24
Q

babesiosis
location

transmission

A

worldwide
northeastern US

transmitted by ticks and blood transfusion

25
babesiosis | life cycle
ticks feed on humans-> get merozoites develop into sporozoites sporozoites injected into new human host during next blood meal
26
babesiosis | what infects us
sporozoites -> turn into merozoites which invade other erythrocytes multiply and release more merozoites
27
babesiosis | path
merozoites live intracellularly in erythrocytes, they multiply and cause cells to burst causing hemolytic anemia, thrombocytopenia hemoglobinuria and RF
28
babesiosis | which one is fatal/ which is self limiting
b. divergens- fatal in splenectomized patients | b. microti- self limiting
29
babesiosis | immunity
partial
30
babesiosis | ss
jaundice | fever chills headache malaise anorexia myalgia
31
babesiosis | dx
pear shaped merozoites in infected RBCs | mallets cross sign inside RBC
32
babesiosis | tx
clyndamycin and quinine
33
Malaria cause transmission by
``` plasmodium flacifarum (kills most people) plasmodium vivax (most common in US) ``` (protozoan) female anophelees mosquito
34
Malaria | stats
``` #1 killing parasite infection 200-300 million and kills 1 million ``` couple cases in US but not and endemic
35
Malaria | life cycle
mosquitos inject sporozoites go to liver-> form merozoites merozoites invade erythrocytes and multiply gametoxutes develop as well which are picked up by mosquitoo and reproduction occurs in mosquito
36
Malaria | path
rupture of schizonts releasing merozoites from RBC result in liver and anemia removal of waste results in enlargement of liver and spleen
37
malaria | immunity
partial protective immunity to species resistance to vivax- via absence of duffy a and b sickle cell blocks binding of plasmodium falciparum
38
Malaria | ss
``` chills fever headache backache renal failure splenomegaly keratitis photophobia ```
39
Malaria | dx
merozoites schizonts gametocytes seen in blood smears
40
Malaria | tx
cloroquine- vivax primaquine- falciparum doxy- prophylaxis
41
American trypanosomiasis epi transmission
``` trypanozoma cruzi (protozoan) American (armadillos ) ``` transmission via feces of reduviid bug NOT the bite of the bug (also mom to fetus and blood transfusions)
42
American trypanosomiasis | life cycle
metacyclic trip enter and amastigotes develop intracellularly trupomastogote forms in blood / CNS
43
American trypanosomiasis | path
destruction via the growth of amastigones in tissues (like heart and muscle) causing destruction of structure and modifying heart contractions
44
American trypanosomiasis | ss
Romanos sign (swollen eye) fever edema meningoencephalitis cardiac problems - (heart ENLARGES to compensate, also megacolon)
45
American trypanosomiasis | dx
triatomic bugs feed on patient and identify metacyclci trypomastigones in fecal smears from bug
46
American trypanosomiasis | tx
nifurtimox
47
Filariasis | cause
brugia malayi wuchereria bancrofti (nematode)
48
Filariasis | epi
found in tropical areas of the world malayi- humans and non humans bancrofti- humans only
49
Filariasis | life cycle
from mosquitoes into humans in a bite microfilaria leave mosquitos and turn into adult worms in the lymph of humans mosquitos infected 12-14 days after a blood meal
50
Filariasis | path
slowing of lymph causes inflammation of lymphatic vessels
51
Filariasis | ss
chills fever wheezing coughing chronic lymphedema enlarged lymph nodes and lymphangitis Years of exposure- elephantiasis of limbs and genitals
52
Filariasis | dx
microfilaria- in sac like death in lymph node biopsies
53
Filariasis | tx
diethylcarbamazine