Respiratory Flashcards
What is Croup?
Viral laryngotracheobronchitis.
What are the risk factors for croup?
- FHx
- LBW / Prematurity
- Autumn / Winter
- M > F
What are the causes of croup?
- Main cause = Parainfluenza
- Other causes
- RSV
- Rhinovirus
- Influenza
What are the signs and symptoms of croup?
- Affects 6 months to 6 years → 2 years = peak
- Acute onset of - over days
- Coryzal symptoms
- “Barking cough” - from vocal cord impairment
- Stridor - from inflamed/oedematous airways
- Hoarse voice
What are the appropriate investigations for suspected croup?
- Clinical
- Obs
- Do NOT examine throat
How is croup classified?
Westley score
- Mild = 0-2
- Moderate = 3-7
- Severe = 8-11
- Impending respiratory failure = 12-17
What is the management of croup?
- Mild (Westley 0-2) = Oral Dexamethasone + Discharge
- Moderate (Westley 3-7) = Nebulised Dexamethasone + Admission
- Severe (Westley 8-11) = Nebulised Dexamethasone ± Adrenaline + Admission
- Impending respiratory failure (RR >70 and/or Westley 12-17) = Nebulised Dexamethasone ± Nebulised Adrenaline + O2 Admission ± ITU
What are the complications of croup?
- Secondary bacterial superinfection
- Pulmonary oedema
- Pneumothorax
What counselling should be given to child/parents with a child with croup?
- Explain diagnosis -common viral infection of the airways
-
Explain that it gets better over 48 hours and steroids help
- Paracetamol or ibuprofen if distressed
- Advise good fluid intake
- Safety net:
- Advise regularly checking on the child at night - cough is worse
- If it gets worse = come back
- If the child becomes blue or very pale for more than a few seconds, unusually sleepy or unresponsive or serious breathing difficulties call an ambulance
What are the causes of bronchiolitis?
- RSV (80%)
- Parainfluenza
- Rhinovirus
- Adenovirus
- Influenza
- Human metapneumovirus (rare → PICU care)
- Co-infection = more severe illness
- RSV highly infectious so infection control measures
What is the progression of bronchiolitis?
Bronchiolitis (0-1yo) → Viral-induced/episodic Wheeze (1-5yo) → Asthma (>5yo)
What are the risk factors for bronchiolitis?
- Pre-term/BPD
- Passive smoking
- LBW
- Chronic heart disease
- Hypotonia
- Winter
- Protective = BREASTFEEDING
What are the complications of bronciolitis?
Can cause permanent airway damage - bronchiolitis obliterans
- Rare
What are the signs and symptoms of bronchiolitis?
- <1 year old → 2-3% of infants are admitted with it
- Coryzal symptoms → progressive to below
- Dry wheezy cough
- SoB
- Grunting
- High RR/HR
- Subcostal/intercostal recessions
- Hyperinflation
- Auscultate – how to differentiate from croup/other ‘-itits’
- Fine, bi-basal, end-inspiratory crackles
- High-pitch expiratory wheeze
- Feeding difficulty → admission
What are the appropriate investigations for?
- Clinical diagnosis with SpO2 → can do NPA to confirm
- If there is significant respiratory distress + fever = CXR to rule out pneumonia
What is the management of bronchiolitis?
-
Supportive
- Nasal O2 + NG fluids/feeds ± Nebulised 3% saline → CPAP (if respiratory failure)
- <6m old = no beta receptors in lungs so salbutamol won’t work – would give it if over 1yo
- If high-risk preterm infant (BPD, congenital HD, immunodeficiency) = Palivizumab (monoclonal Ab vs RSV)
- Hospital admission
- <2m = lower threshold as deteriorate quick
- Apnoea / Central cyanosis / Grunting
- SpO2 <92% on room air
- Poor oral fluid intake (≤50% normal in <24hrs)
- Severe respiratory distress (i.e. RR>70)
Define Rhinitis.
Common cold causing acute and self-limiting inflammation of URT mucosa, involving nose, throat, sinuses or larynx.
What is the most common infection in childhood?
Rhinitis
What are the causes of rhinitis?
- Rhinovirus (50%)
- Coronavirus (10%)
- Influenza (5%)
- Parainfluenza (5%)
- Human respiratory syncytial virus (5%)
What are the signs and symptoms of rhinitis?
- Clear/mucopurulent discharge
- Nasal block
What are the appropriate investigations for suspected rhinitis?
Clinical diagnosis
What is the management of rhinitis?
-
Health education
- Self-limiting
- No Abx - virus
- May reduce anxiety and unnecessary visits to doctor
- Cough may last 4 weeks after cold → generally recover after 2 weeks
- Pain = Paracetamol or Ibuprofen
- Potentially Decongestants or Antihistamines
What are the complications of rhinitis?
- Otitis media
- Acute sinusitis
Define Sinusitis.
Infection of the maxillary sinuses from viral URTIs which can get a secondary bacterial infection.
- Unlikely to be frontal sinus → don’t develop until after 10 years old
What are the signs and symptoms of sinusitis?
- Pain, swelling and tenderness on front of face
- Influenza-like illness
What are the appropriate investigations for suspected sinusitits?
Clinical diagnosis
What is the management of sinusitis?
- Symptoms lasting <10 days
- No antibiotic
- Advice → virus, takes 2-3 weeks to resolve, only 2% get bacterial complication, simple analgesia, nasal saline or nasal decongestants
- Symptoms lasting >10 days
-
High-dose nasal corticosteroid for 14 days (if >12yo; e.g. mometasone)
- May improve symptoms but unlikely to affect duration of illness
- Abx not indicated → can give back up prescription if symptoms don’t get better in 7 days or if symptoms get rapidly worse
- 1st line = phenoxymethylpenicillin (clarithromycin if penicillin-allergic)
- 2nd line: co-amoxiclav
-
High-dose nasal corticosteroid for 14 days (if >12yo; e.g. mometasone)
- Refer to hospital if there are symptoms and signs of
- Severe systemic infection
- Intraorbital or periorbital problems
- Intracranial complications / Features of meningitis
What are the risk factors for viral-induced wheeze?
- Maternal smoking (ante-/post-natal)
- Prematurity
- FHx of viral-induced wheeze
What are the signs and symptoms of asthma?
- Wheeze - end-expiratory polyphonic
- Cough
- SoB
-
Chest tightness
- Symptoms worst at night / early morning
- Symptoms with non-viral triggers
- Personal or FHx of atopy
- Positive response to asthma bronchodilator therapy
- Examination
- Hyperinflated chest ± accessory muscle use
- Harrison’s sulci - depressions at base of thorax where diaphragm has grown in muscular size
What are the appropriate investigations in to suspected asthma in a child under the age of 5?
Clinical diagnosis
What are the appropriate investigations in to suspected asthma in a child over the age of 5?
-
Clinical + Picture
- Spirometry - FEV1/FVC <70%
- Bronchodilator - 12% pre/post difference
What are the signs of a moderate asthma attack in a child?
- PEFR = 50-75%
- Normal speech
What are the signs of a severe asthma attack in a child?
- PEFR = 33-50%
- RR
- 2-5 years = >40
- 5-12 years = >30
- >12 years = >25
- HR
- 2-5 years = >140
- 5-12 years = >125
- >12 years = >110
- SpO2 = >92%
- Inability to complete sentences in one breath
- Accessory muscle use
- Inability to feed
What are the signs of a life-threatening asthma attack in a child?
- PEFR = <33%
- SpO2 = <92%
- PaCO2 = >4.8kPa
- Altered consciousness
- Exhaustion
- Cardiac arrhythmia
- Hypotension
- Cyanosis
- Poor respiratory effort
- Silent chest
What is the management of a moderate asthma attack?
- No admission needed
- Salbutamol - 4-hourly up to max 4/day
- Oral prednisolone - for 3d
- Follow-up in 48hrs
What is the management of a severe to life-threatening asthma attack?
- Admit to hospital/A&E
- Burst step
* O2 therapy (maintain SpO2 >92%)
* 3x Salbutamol nebs / 10 inhales on a pump
* 2x Ipratropium bromide nebulisers
* 1x oral Prednisolone (benefit after 4-6h)
- Burst step
- IV bolus step
* IV bolus MgSO4 + one of the below
* IV bolus Salbutamol
* IV bolus Aminophylline- Monitor ECG → both can cause arrhythmias
- IV bolus step
- IV infusion step – one of the below
* IV Salbutamol
* IV Aminophylline
- IV infusion step – one of the below
- Panic step
* Intubate and ventilate + Transfer to ICU
- Panic step
- Once stabilised = Salbutamol 1-hourly → 2-hourly → 3-hourly → 4-hourly → Home when:
- Stable on 4-hourly treatment - further wean at home
- Peak flow at 75% of best predicted
- SpO2>94%
- Follow-up within 2 days of discharge
- Patient Education
What are the contraindications for beta-agonists (salbutamol)?
- Beta blockers
- NSAIDs
- Adenosine
- ACEi
What is the outpatient management of asthma in a child?
-
SABA - Salbutamol PRN → Step up when using inhaler ≥3x a week
- Can use a spacer if young or difficulty using
- Do not exceed 4-hourly puffs (i.e. 4 puffs a day)
- Low dose ICS - Becotide (Beclomatsone dipropionate)
-
Leukotriene Receptor Antagonist - Oral Montelukast
- Review after 4-8w
- 5-16yo = if fail on review, switch LTRA to LABA
- <5yo = if fail on review, stop LTRA and refer to specialist
- Review after 4-8w
-
Increased ICS dose - Flixotide (Fluticasone propionate)
- Consider reducing dose once asthma controlled
-
Oral steroid - Prednisolone
- Lowest dose to maintain control
- Managed by specialist
How common is acute otitis media?
- Very common - Most children have 1 episode
- Young eustachian tubes are short, horizontal and function poorly → middle ear infection
What are the risk factors for acute otitis media?
- 6-12 months
- FHx
- Male
- Cleft palate
- Down’s
- Most children have at least one episode
What are the signs and symptoms acute otitis media without effusion?
- Pain in the ear
- Fever
What are the appropriate investigations for suspected acute otitis media without effusion?
- Temperature check
- Otoscopy
- Bright red bulging tympanic membranes
- Loss of normal light reaction
- Perforation
- Pus
What is the management of acute otitis media without effusion?
- Advice
- Acute otitis media lasts about 3 days (up to 1 week)
- Most recover without Abx
- Use regular ibuprofen/paracetamol
- No evidence for decongestants or antihistamines
- Medical Management / Antibiotic regimen
-
No antibiotic prescription → seek help if symptoms haven’t improved after 3 days or clinical deterioration
- Delayed antibiotic prescription used at this point
- Immediate antibiotic prescription if systemically unwell, age <2yo
- Amoxicillin (5 days) → penicillin allergy = clarithromycin, erythromycin
-
No antibiotic prescription → seek help if symptoms haven’t improved after 3 days or clinical deterioration
What is the management of acute otitis media with perforation?
- Oral Amoxicillin - 5 days
- Review in 6 weeks to ensure healing
What are the signs and symptoms of otitis media with effusion?
- Asymptomatic except for possible reduced hearing - conductive hearing loss
- Can interfere with normal speech development → learning difficulties
What are the appropriate investigations for suspected otitis media with effusion?
- Tympanometry
- Audiometry
- Otoscopy - eardrum is dull and retracted, often with a fluid level visible
What is the management of otitis media with effusion?
- Co-existent cleft palate, Down’s, hearing loss, structurally abnormal tympanic membrane or cholesteatoma discharge → refer to ENT
- No co-morbidities à active observation for 6-12 weeks
- 1) Two hearing tests (pure tone audiometry) 3 months apart
- 2) If persistent past 6-12 weeks → refer to ENT
- Non-surgical = Hearing aids, Active monitor for 3m, Auto-inflation
- Surgical = Myringotomy and Grommets
- Benefits don’t last longer than 12 months
What are the complications of acute otitis media?
- Perforation
- Mastoiditis
- Meningitis
- Facial nerve palsies
- Febrile convulsions
Describe Mastoiditis.
Chronic otitis media → honeycomb structure behind ear inflamed → Discharge + Swelling behind ear
What are the diagnosis for the following otoscopy examinations?
What counselling should be given to child/parents with a child with pneumonia?
- Explain the diagnosis - chest infection
- Explain whether admission is needed
- Explain treatment - antibiotics
-
Advise:
- Paracetamol used if distressed
- Adequate fluid intake
- Against parental smoking
- Check the child regularly during the day and night
-
Safety net
- ↑ RR
- Apnoea
- Cyanosis
- ↑ WOB
- Dehydration
- Fever does not settle 48h+ of AbX
- ↑ Drowsy
What are the consequences of Group A Strep tonsillitis?
Scarlet Fever → can progress to Rheumatic fever
What are the signs and symptoms of Scarlet fever?
-
After 2-4 day incubation
- Fever
- Headache
- Vomiting
- Myalgia
-
Rash (12-48 hours later) ± erythroderma
- Neck + chest → spread to trunk + legs
- Characteristic ‘sandpaper’ texture
- ‘Pastia’s lines’ (rash in prominent skin creases)
- Strawberry tongue
- May progress to Rheumatic Fever with a week latency period
What are the appropriate investigations for suspected Scarlet fever?
- Clinical
- FBC (polymorphonuclear lymphocytosis, eosinophilia)
- ELISA
- Rapid antigen test
What is the management of Scarlet fever?
- Phenoxymethylpenicillin
- 2nd line = Azithromycin
- Notify PHE
What are the causes of pneumonia in children?
- Neonate = Mother’s genital tract commensals = GBS, gram -ve enterococci
- Infants / Young children = RSV, S. pneumoniae, H. influenzae, Bordetella pertussis, C. trachomatis, S. aureus
- >5yo = M. pneumoniae, S. pneumoniae, Chlamydia pneumoniae
- All ages = Mycobacterium tuberculosis should be considered
What are the signs and symptoms of pneumonia?
- Fever
- Cough
- SoB
- Preceding URTI
- Auscultation
- Consolidation - stony dull, bronchial breathing, decreased breath sounds
- Coarse crackles
What are the appropriate investigations for suspected pneumonia?
- Basic obs - temperature, O2 saturations, RR, respiratory exam
- Bloods - FBC, U&Es
- Cyanosis and hydration status
- VBG
- CXR
What are the appropriate investigations for suspected childhood TB?
- Manteaux test → if -ve = excludes → IGRA test (if -ve, prophylaxis; if +ve, treat)
- Manteaux >5mm = +ve in immunodeficiency
- Manteaux >10mm = +ve in at-risk groups (child <4yo, healthcare workers, IVDU)
- Manteaux >15mm = +ve in normal population
What is the management of childhood TB?
- RIPE = 6m Rifampicin, 6m Isoniazid, 2m Pyrazinamide, 2m Ethambutol
- RiCES = Rifampicin, Clarithromycin, Ethambutol ± Streptomycin/amikacin
- Prophylaxis = isoniazid
What examination findings can distinguish between pneumonia and bronchiolitis?
- Pneumonia = coarse crackles
- Bronchiolitis = fine crackles
What is the management of pneumonia?
- Antibiotics
- Child <2yo with mild LRTI → do not have pneumonia usually = No antibiotics
- 1st line = Amoxicillin (7-14 days)
- 2nd line = Co-amoxiclav + Macrolides (clarithromycin)
- Alternative = cefaclor
- Macrolides for pen-allergic patients
- In pneumonia associated with influenzae → co-amoxiclav
- Supplementary O2 - if SpO2 <92%
What are the indications for hospital admission of a child with a respiratory condition?
- SpO2 <92% on air
- Grunting
- Marked chest recession
- RR >60/min (severe tachypnoea)
- Cyanosis
- T >38oC
- Child <3months
- Low feeding
- Low consciousness
What counselling should be given to parents with a child with tonsillitis?
- Explain that this is tonsillitis → Centor score the child
- Explain that importance of taking antibiotics correctly for 10 days even if symptoms get better in that time
- Avoid school until 24 hours after starting antibiotics and the child is feeling well
- Advise on the use of paracetamol, lozenges, saltwater gargling and Difflam for symptomatic treatment
What are the causes of tonsillitis?
- Bacterial → Group A β-haemolytic streptococcus – rare under 3yo or ≥45yo, common 3-14yo
- Viral → EBV
What shouldn’t be given to patients with EBV?
Amoxicillin → can get generalised maculopapular eruption
What are the signs and symptoms of tonsillitis (pharyngitis and laryngitis)?
- Sore throat
- Fever
- Dysphagia/odynophagia
- Hoarseness
- GORD
- Rhinitis
- Lethargy / fatigue
- Post-nasal drip
- Laryngitis - dysphonia, aphonia
What are the appropriate investigations for suspected tonsillitis?
- ENT exam + temperature
- Rapid strep test
-
Centor score - likelihood of bacterial cause
- +1 = Exudate/swelling on tonsils
- +1 = Tender/swollen anterior cervical lymph nodes
- +1 = Temperature >38C
- +1 = Cough absent
- +1 = Age 3-14yo → -1 if age ≥45yo
- Consider swabs
What is the management of tonsillitis?
-
Medical Management
- Bacterial tonsillitis confirmed using rapid streptococcal antigen testing = Phenoxymethylpenicillin
- 10 days, QDS → prevent sequelae like rheumatic fever
- Avoid amoxicillin = widespread maculopapular rash if due to mono
- Clarithromycin if pen-allergic
- Bacterial tonsillitis confirmed using rapid streptococcal antigen testing = Phenoxymethylpenicillin
-
Advice
- Adequate fluid intake
- Paracetamol or ibuprofen when necessary
- Saltwater gargling
- Lozenges or anaesthetic sprays (e.g. Difflam)
What are the indicators for tonsillitis admission?
- Difficulty breathing
- Clinical dehydration
- Peri-tonsillar abscess or cellulitis
- Marked systemic illness or sepsis
- Suspected rare cause → e.g. Kawasaki disease, diphtheria
What is Cystic Fibrosis?
- Defective CFTR – cAMP dependent chloride channel due to a mutation on chromosome 7
- >900 different gene mutations of CFTR → 78% are F508
- Class 2 mutation = incorrect folding of CFTR protein
- >900 different gene mutations of CFTR → 78% are F508
What are the signs and symptoms of cystic fibrosis?
- Meconium ileus
- Recurring chest infections, wheezing, coughing, SoB, damage to the airways (bronchiectasis)
- Growth faltering (difficulty putting on weight)
- ABPA, nasal polyps, sinusitis
- Jaundice (cirrhosis, portal HTN)
- Diarrhoea or constipation
- Diabetes mellitus
- Male sterility (absence of the vas deferens)
- Clubbing of the fingers
What are the appropriate investigations for suspected cystic fibrosis?
- Screening at birth = heel prick test for IRP / Immunoreactive Trypsinogen (if +ve, further tests are done) →
- Sweat test (abnormally high NaCl in sweat) → 60-115mmol/L (10-40mmol/L)
- Genetic tests
- CXR → hyperinflation, peri-bronchial shadowing, bronchial wall thickening, ring shadows
What is the management of cystic fibrosis?
- MDT - all should be specialists in CF
-
Routine specialist reviews
- Weekly in 1st month
- Every 4w in 1st year
- Every 6-8w when 1-5yo
- Every 2-3m when 5-12yo
- Every 3-6 months from then on
- RESPIRATORY Management:
- Monitoring with spirometry and symptoms watches
- Physiotherapy twice a day → airway clearance manoeuvres and devices + encourage physical activity
-
Mucolytic therapy
- 1st line = rhDNase
- If too young use mannitol dry powder
- 2nd line = rhDNase + hypertonic saline
- Orkambi - Lumacaftor with Ivacaftor (potentiators and correctors) → may be effective in prolonging life in F508 mutation
- 1st line = rhDNase
-
Trikafta - 3 drug combination → 2 drugs allow F508del-misfolded CFTRs to get to cell surface, the 3rd allows the protein to fold properly
- Available on NHS but is expensive and not in NICE guidlines
- Lung transplant
- NUTRITIONAL Management:
- High calorie + high fat diet (150% of normal) + fat-soluble vitamin supplements
- Pancreatic enzyme replacement
- PYCHOLOGICAL Management
- GENERAL TEENAGERS and ADULTS Management:
- DM therapy - becoming more common as CF live longer
- Liver problems (i.e. cirrhosis, portal HTN) = Ursodeoxycholic acid, laxatives → may ultimately require transplantation
- Sterility → intracytoplasmic sperm injection (only affects men)
What is the management of infection in CF?
- Prophylaxis oral antibiotics (flucloxacillin and azithromycin to reduce exacerbation chance)
- Rescue packs → prompt IV Abx with any symptoms or signs of infection
- Appropriate Abx for sensitivity
- Minimise contact with other CF sufferers when infected
What are the common infections in cystic fibrosis?
- S. aureus
- P. aeruginosa
- Burkholderia cepacia complex
- H. influenzae
- Non-tuberculosis mycobacterium
- Aspergillus fumigatus
- Prophyla
What counselling should be given to parents with a child with cystic fibrosis?
- Explain the diagnosis - thick secretions
- Explain it is lifelong
- Explain that that management requires an MDT approach
- Explain that they will be referred to a specialist cystic fibrosis centre to discuss the ongoing management
- Offer to outline the aspects of management
- Pulmonary – physiotherapy, mucolytics
- Infection – prophylactic antibiotics, monitoring
- Nutrition – enzyme tablets, high-calorie diet, monitor growth
- Psychosocial – provide support for child and carers
- Offer information on genetic counselling if considering having more children
- Support groups - Cystic Fibrosis Trust
Define Acute Epiglottis.
Intense swelling of epiglottis associated with sepsis → Medical Emergency
What are the signs and symptoms of acute epiglottis?
- High fever - ‘toxic-looking’ child
- Drooling → child cannot swallow as too sore
- Stridor - soft inspiratory with high RR
-
Tripod sign
- Immobile
- Upright
- Open mouth
What is the management/investigations for acute epiglottis?
-
MEDICAL EMERGENCY
- Do not lie the child down - immobile and upright stance is optimal
- Do not examine the child’s throat → may precipitate total obstruction
-
Immediate referral to ENT, paediatrics and anaesthetics → Transfer to ITU/anaesthetics
- Secure airway
- Blood cultures
- Empirical ABx ± Dexamethasone
- Most children recover in 2-3 days
- Rifampicin given to close household contacts as prophylaxis
Define Otitis externa.
Inflammation of the outer ear – auricle, external auditory canal and outer surface of eardrum
What are the types of otitis externa?
-
Acute diffuse otitis externa (Swimmer’s ear)
- Moderate temperature and lymphadenopathy, diffuse swelling, variable pain and pruritus, moving ear/jaw is painful, impaired hearing
- Bacterial infection common
-
Chronic otitis externa
- Discharge and itch are common
- Fungal and associated with underlying skin conditions, diabetes, immunosuppression
-
Necrotising otitis externa = Life-threatening extension into mastoid and temporal bones → urgent ENT referral
- Pain, oedema, exudate, micro abscess, granulation tissue, pseudomonas culture
- Mainly due to P. aeruginosa or S. aureus
- Mainly in elderly
What are the risk factors for otitis externa?
- Hot and humid climates
- Swimming
- Older age
- Immunocompromised
- Diabetes
- Wax build-up
- Narrow external canal
- Obstruction of canal
- Insufficient wax - predispose infection
What are the appropriate investigations for suspected otitis externa?
Swabs and Culture
What is the management of acute otitis externa?
- Topical drops of
- Acetic acid - only effective for 1 week
- Antibiotics - neomycin or clioquinol
- Wicking and removal of debris
- If the above fails → reconsider diagnosis
- If cellulitis or cervical lymphadenopathy → oral antibiotics
Define Laryngomalacia.
Congenital abnormality of larynx cartilage predisposing to supraglottic collapse during inspiration.
What are the signs and symptoms of laryngomalacia?
- 2-6 weeks old = Noisy respiration and Inspiratory stridor
- Worse → supine, when feeding or if agitated
- Not present at birth
- GORD ± feeding difficulties
- Cough/choking
- Normal cry → no abnormality with vocal cords
- Baby otherwise comfortable
What are the appropriate investigations for laryngomalacia?
- O2 monitor
- Flexible laryngoscopy
What is the management of laryngomalacia?
-
Conservative → close observation and monitoring of growth
- Usually resolve by 18-24 months (70% by 1-year-old)
- May initially worsen with age, max at 6-8 months
- Endoscopic supraglottoplasty - if airway compromise or feeding disrupted sufficiently to prevent normal growth
What are the complications of laryngomalacia?
- Respiratory distress
- Failure to thrive
- Cyanosis
What is chronic lung disease (Bronchopulmonary dysplasia)?
- Lung damage in the newborn / child due to:
- Delay in lung maturation (i.e. premature)
- Pressure and volume trauma from artificial ventilation
- Oxygen toxicity
- Infection
What are the appropriate investigations for suspected chronic lung disease (Bronchopulmonary dysplasia)?
Chest X-Ray = widespread opacification
What is the management of chronic lung disease (Bronchopulmonary dysplasia)?
- O2 requirements
- Artificial ventilation (in bad CLD)
- CPAP or high-flow nasal cannula (normal CLD)
- Corticosteroids
- Low-dose for short course
What causes Whooping cough?
Bordetella pertussis → gram -ve bacteria
What are the risk factors for whooping cough?
Unvaccinated → included in the 6-in-1
What are the signs and symptoms of whooping cough?
- 1-week coryzal symptoms followed by
- Continuous coughing followed by inspiratory whoop
- Vomiting
- Epistaxis
- Conjunctival haemorrhages
- Child = worst at night, may go red/blue
- Infants = apnoea rather than a whoop
What are the appropriate investigations for suspected whooping cough?
- Culture ± PCR - Naso-Pharyngeal Aspirate for Bordetella pertussis
- Notify HPU
What is the management of whooping cough?
-
Antibiotics
- <1 month = oral clarithromycin
- >1 month = oral azithromycin
- 2nd line = co-amoxiclav
- Advice
- Rest, fluids, paracetamol or ibuprofen
-
Educate parents
- Disease is likely to cause a protracted non-infectious cough → may take weeks to resolve
- Complete any outstanding immunisations
- Cose contacts prophylaxis macrolides
- Avoid nursery until 48 hours of antibiotics or until 21 days after the onset of the cough if not treated
- Admit
- <6mo
- Acutely unwell
- Significant breathing difficulty
- Significant complications → e.g. seizures, pneumonia
What counselling should be given to parents with a child with whooping cough?
- Explain the diagnosis - cough that lasts for a reasonably long time
- Explain it’s uncommon because of the immunisation - discuss concerns about immunisation with the parent
- Explain you can have it again
- Explain the treatment = antibiotics but cough often persists for a long time
- Exclude from school until 48 hours after starting antibiotics