respiration lec 1 Flashcards

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1
Q

How do the various laws of physics affect transportation of oxygen and carbon dioxide within the respiratory system?

A
fick equation-diffusion rates
ideal gas law - gas pressure
dalton's law of partial pressures
henry's law - dissolving gases in liquid
graham's law - rate of diffusion
boyle's law - volume vs pressure
resistance to bulk flow
surface area geometry - SA:volume ratios
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2
Q

How does an animal’s size affect its mode of gas transport?

A

larger cannot rely on diffusion, due to volume increasing more than SA, so must rely on bulk flow aswell via systems

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3
Q

What are the 4 general types/models of respiration?

A

way of the small
embracing the environment
way of the skin
mass transit

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4
Q

Why is measurement of partial pressure important when discussing gas transport?

A

because air is not pure oxygen

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5
Q

What physical factors affect diffusion rates, and how does this relate to respiratory organs/systems?

A

.increases with diffusion coefficient of medium
surface area
pressure gradient
solubility
decreases withdiffusion distance and molecular weight

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6
Q

 What are some of the important physical differences between air and water as they relate to gas exchange?

A

-O2 must dissolve and then diffuse when travelling from air to water of the cell

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7
Q

What are the three main physical processes that govern transportation of gases to and from the mitochondria?

A

dissolution: from environment to body
diffusion: body to cell
bulk flow: environ into trachea (ie in bugs)

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8
Q

respiratory system summary

A

one goal
two mediums
three processes
four systems

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9
Q

way of the small

A
  • diffusion over small area

- ie. cellular respiration

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10
Q

embracing the environment

A

flow of external medium (air or water) through the body

ie. water flowing out of a sponge, or air into an insect through spiracles; oxygen bathes/bulk flows over the cells

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11
Q

way of the skin

A

aka cutaneous respiration/diffusion, followed by internal circulation which distributes O2 to the cells via bulk flow

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12
Q

mass transit

A

bulk flow into specialized system, then bulk flow in internal circulation distributes O2

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13
Q

diffusion

A

movement of molecules from high conc to low conc

-slow over long distances but fast over short distances

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14
Q

Fick equation

A
  • diffusion rate of gases is proportional to diffusion coefficient, area of the membrane, and diff in pressure over distance
  • to max diffusion respiratory surface are THIN with LARGE SA and rely on high diffusion gradients
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15
Q

ideal gas law

A

pressure of a gas is equal to the number of moles of gas and the volume the occupy (PV=nRT)

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16
Q

dalton’s law of partial pressure

A

air does not equal oxygen

  • in a gas mixture each gas exerts its own partial pressure
  • sum of all partial pressures is equal to the total of the mix
  • Ptotal= Po2+Pco2
17
Q

henry’s law

A
  • gas molecules in the air must first dissolve in liquid to diffuse into cells
  • concentration of gas in a liquid is proportial to its partial pressure and solubility
  • henrys law= [G]= Pgas*Sgas
18
Q

diffusion rates: grahams law

A

solubility of a substance is the amount of that substance that will dissolve in a given amount of solvent

19
Q

rate of diffusion at specific temp in specific medium increases with

A

diffusion coefficient of medium
surface area
pressure gradient
solubility

20
Q

rate of diffusion at specific temp decreases with

A

diffusion distance and molecular weight

21
Q

boyles law/bulk flow of gases

A

PV=PV

  • initial pressure and volume=final pressure and volume
  • for respiration that means liquids and gases both move from an area of higher pressure to an area of lower pressure
  • in bulk flow think of a pump filling with water when area available expands
22
Q

resistance of bulk flow

A

rate of flow determind by diff in pressure and resistance: Q=P/R
-resistance decreases with radius, and increases with length and viscosity

23
Q

surface area geometry

A

higher sa-vol ratio the better

  • as radius increases, volume increases faster than SA, and as organisms grow, the ratio decreases
  • bigger means limited surface area available for diffusion and increases diffusion distance/time: t=x^2/4D
  • thus only small organisms can rely only on diffusion of oxygen
24
Q

other problems with diffusion

A

surface must be moist and requires a boundary layer

-larger organisms rely on bulk flow and diffusion, and thus need a proper respiratory system