Respiration During Exercise Part 3 W7 Flashcards

1
Q

What is Daltons Law about partial pressure of gases?

A

The total pressure of a gas mixture is equal to the sum of the pressure that each gas would exert independently

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2
Q

What is the partial pressure of inspired O2?

A

159mmHg

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3
Q

What is the partial pressure of CO2?

A

0.3mmHg

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4
Q

How is O2 consumed and CO2 is produced by tissues?

A

Via cellular respiration

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5
Q

What is PO2 decreased to during inspiration?

A

40mmHg

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6
Q

What is venous PCO2 increased during inspiration?

A

46mmHg

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7
Q

What is mean pulmonary artery pressure?

A

15mmHg

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8
Q

What are 2 key characteristics of pulmonary circulation?

A

Low pressure, low resistance circuit
Thin walled, little smooth muscle

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9
Q

What is mean systemic arterial pressure?

A

100mmHg

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10
Q

What does having thin walled, little smooth muscle allow for during pulmonary circulation?

A

Accepts entire cardiac output

No redistribution of blood flow

Pulmonary vascular resistance decreases during exercise due to recruitment and distension of pulmonary capillaries

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11
Q

What is V/Q?

A

Matching of ventilation to blood flow

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12
Q

What does V/Q>1 indicate?

A

Under perfused (apex of lung)

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13
Q

What does V/Q<1 indicate?

A

Over perfused (base of lung)

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14
Q

Why does blood flow increase disproportional more in the upper right lung compared to ventilation from the top to bottom of the lung?

A

Gravity

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15
Q

Why does V/Q improve upon exercise?

A

Increased tidal volume
Increased pulmonary artery pressures

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16
Q

What are the 2 forms oxygen s carried in the blood?

A

1) Dissolved (2%)
2) Combined with Haemoglobin (98%)

17
Q

What is Henry’s Law?

A

Amount dissolved is proportional to the partial pressure

18
Q

How much oxygen molecules can a singular haemoglobin molecule transport?

A

4

19
Q

What is the Bohr Effect?

A

A rightward shift in the Oxygen Disassociation Curve due to exercise causing increase in H+, CO2 and core body temperature

20
Q

What is the amount of O2 transported as oxyhaemoglobin dependent upon?

A

Haemoglobin mass

21
Q

What does the Bohr Effect Facilitate?

A

Unloading of O2 to Active Tissue

22
Q

What is myoglobin?

A

O2 binding protein found in skeletal muscle

23
Q

What does myoglobin do?

A

High O2 affinity; unloads at very low PO2 (just a few mmHg)

Shuttles O2 from muscle cell membrane to mitochondria for aerobic respiration

Provides intramuscular O2 storage (reserve)

24
Q

How much more soluble is CO2 compared to O2?

A

20x

25
Q

What 3 forms is CO2 carried in blood?

A

1) Dissolved (10%)

2) Bound to Haemoglobin (20%)

3) Bicarbonate (70%