respiration and diabetes (schmidt) Flashcards
agonist (mimetic drug)
binding to a receptor, stimulation of a cellular response
antagonist (lytic drugs)
binding to a receptor, no cellular response, blocking of agonist effect
partial agonist
partial antagonist
diaphragm
skeletal muscle
inspiration
scalene and sternocleidomastoid muscles, external intercostals and diaphragm
expiration
internal intercostals, abdominal muscles
carotid and aortic chemoreceptors
can measure the co2, o2 and pH levels
chemoreceptors
low pO2 is measured, making potassium channels close so calcium flows in and forces the vesicles to release its content
alveoli
surrounded by blood vessels and cells that do gas exchange
bronchial asthma
permanent inflammation of the lung, smooth muscle cells are highly sensitive ACh making the lung hyperactive
what does the insulin receptor activate
activates tyrosine kinase
tyrosine kinase
phosphorylates tirosine residues in proteins
glut 4
takes up glucose, decreasing blood glucose and brings ATP into the cell
gilbenclamide
a sulfonylurea derivative is a treatment for diabetes. potassium channels opening creates a potential for insulin secretion