cardiovascular system (schmidt)

Question 1

Alpha 2 adrenergic receptor

Answer 1

same as M2 except suppression of noradrenaline release

Question 2

positive chronotrope Na

Answer 2

increased heart rate

Question 3

positive inotrope Ca

Answer 3

increased contractile force

Question 4

beta receptor blockers

Answer 4

sympatholytic drugs, ending with -ol like propranolol

Question 5

which receptors do functional antagonism in smooth muscle cells

Answer 5

M3 and beta2 receptor

Question 6

which receptors do functional antagonism in cardiac muscle

Answer 6

M2 and beta1 receptor

Question 7

which receptor acts in skeletal muscle

Answer 7

nicotinic receptor, acts very fast and binds ACh and is a sodium channel

Question 8

which receptors are important in ACh release

Answer 8

M2 and alpha 2

Question 9

which receptors are in the heart

Answer 9

beta1 adrenoreceptors

Question 10

which receptors are in the blood vessels

Answer 10

alpha1/beta2 adrenoreceptors, alpha 1 sympatholytic, beta1,2 sympatholytic

Question 11

blocking beta 2 receptor will cause

Answer 11

reduces blood vessel diameter

Question 12

cardiac glucoside effect

Answer 12

causes a higher contractility so risk for cardiac arythmia

Question 13

nitrates

Answer 13

produced under demand of M3 receptor, vasodilator

Question 14

artherosclerosis

Answer 14

reduced production of NO, reduced activation of guanylyl cyclase, reduced relaxation of vascular smooth muscle cells