Respiration and carbohydrates Flashcards
Respiration definition
Cells break down food molecules and release the energy they contain
Glycolysis
Occurs in cytoplasm where glucose is broken down into pyruvate
Pyruvate fermentation
Under anaerobic conditions pyruvate is fermented and NADH is recycled
What is the mitochondrial matrix?
- Pyruvate enters under aerobic conditions
- Pyruvate is decarboxylated to produce acetyl CoA for TCA cycle
What is the TCA cycle?
The second stage of cellular respiration
What is produced in the TCA cycle?
- 3 NADH
- 1 FADH2
- 1 ATP
- Release of 2 CO2 molecules
The electron transport chain
- Located in the inner mitochondrial membrane
- NADH and FADH2 are oxidised back to HAD and FAD
- Electrons from NADH pass down a series of electron carriers and are donated to oxygen
- Protons are pumped out of the mitochondria to produce ATP
How many protons are needed for ATP production?
4
How is the TCA cycle controlled?
- Pyruvate dehydrogenase is inhibited by ATP, acetyl CoA and NADH
- Isocitrate dehydrogenase is inhibited by NADH and ATP but activated by ADP
- Ketoglutarate dehydrogenase is inhibited by NADH, ATP and succinyl CoA
How is glycolysis controlled?
Feedback regulation allows cells to switch from glucose breakdown to synthesis
What is glycogenesis?
Generation of glucose from non-carbohydrate sources
Function of glucogenesis
Maintain blood glucose levels in liver and kidney
Lactase
Made from glucose and galactose
Maltose
Made from 2 glucose molecules
Trehalose
Made from 2 units of glucose but with a different glycosidic bond