Respiration Flashcards
Functional Residual Capacity (FRC) Is
- Amount of gas in the lungs at the end of a passive expiration
- Neutral or equilibrium point for the Respiratory System
FRC is the marker for
Lung compliance
Inspiratory capacity (IC) is
Maximal volume of gas that can be inspired from FRC
So bottom of TV to the very top
Inspiratory reserve volume (IRV) is
Additional amount of air that can be inhaled after normal inspiration
So, from the top of TV to the max
Expiratory reserve volume (ERV) is
Additional volume that can be expired after a passive expiration
From bottom of TV to the top of RV
Residual volume (RV) is
Amount of air in the lung after a maximal expiration
Vital capacity (VC) is
Maximal volume that can be expired after a maximal inspiration
Total ventilation =
VT X f
Alveolar ventilation =
(VT - DS) X f
What is the net result during inspiration
to make Intrapleural pressure more negative
Lung compliance =
ΔV/ΔP
What will increase lung compliance curve
- Emphysema
- Aging
- Normal Saline in alveoli
What will decrease lung compliance
Fibrosis
FEV1/FVC in restrictive disorders
Normal
FEV1/FVC in obstructive disorders
Decrease
Lab results of Obstructive disorder
- Decrease FVC
- Increase FRC
- Increase TLC
- Increase RV
- Severly decreased FEV
Obstructive is due
Breathing in is normal, but can’t breath out.
Lab results in Restrive disorder
Everything decreases but FEV1/FEV is normal
What does the flow-volume loop look like in obstructive disease
Begns and ends at abnormally high lung volumes
Expiratory flow is lower than normal
Downslope scalops or bows inward
Each g of Hb can combine with
1.34 mL of O2
What shifts Oxygen-Hb curve to the right
- Increase CO2
- Decrease pH (Increase H+)
- Increase Temperature
- Increase 2,3-BPG
What shifts Oxygen-Hb curve to the left
- Decrease CO2
- Increase pH (Decrease H+)
- Decrease Temperature
- Decrease 2,3-BPG
Right shift of Oxygen-Hb curve indicates
Reduced affinity of Hb molecule for oxygen
Stimulation of central chemoreceptors locatedin medulla cause
increased ventilation
What governs central chemoreceptors
CSF H+ and CO2
Mainly CO2
Peripheral chemoreceptors found in
Carotid bodies (CN 9)
Aortic bodies (CN 10)
Apneustic breathing is due to
Loss of the normal balance between vagal input and the pons-medullary interactions
Leasion in Caudal pons
Cheyne-Stokes breathing is due
Midbrain lesion or CHF
Ventilation is
Adding Oxygen
Removing Carbond dioxide
Perfusion is
Removing oxygen
Adding Carbon dioxide