Renal Flashcards
Nephron with glomeruli located in
Outer cortex of kidney
Exretion rate (ER) =
(filtration rate - reabsorption rate) + secretion rate
Essential HT increases renal artery P leading to
Vasoconstriction of afferent
Vasodilation of efferent
Constriction of efferent a causes
Increase Glomerular Cap P
Decrease Peritubular Cap P
Decrease Nephron Plasma flow
Dilation of efferent A causes
Decrease Glomerular Cap P
Increase Peritubular Cap P
Increase Nephron Plasma Flow
Constriction of afferent A causes
Decrease Glomerular Cap P
Decrease Peritubular Cap P
Decrease Nephron Plasma flow
Dilation of afferent A causes
Increase Glomerular Cap P
Increase Peritubular Cap P
Increase Nephron Plasma flow
Normal GFR is
120 mL/min
Normal RPF is
600 mL/min
Filtration Fraction (FF)=
GFR/RPF
120/600
.20 or 20%
The greater FF the…
The higher the oncotic pressure in the peritubular capillaries
Afferent contriction affect on GFR, RPF, FF, and Glomerular filtration pressure
- GFR: Decrease
- RPF: Decrease
- FF: Normal
- glomerular filtration P: Decrease
Efferent constriction affect on GFR, RPF, FF, and Glomerular Filtration P
- GFR: Increase
- RPF: Decrease
- FF: Increase
- Glomerular Filtration P: Increase
Affect of Angtiotensin 2 on arterioles
Constricts both afferent and efferent but has a bigger effect on efferent
What are the consequences of Angiotensin 2
- Decrease RPF
- Increase GFR
- Increase FF
- Increase forces promoting reabsorption in the peritubular capillaries
Filtered load=
GFR X Px
Excretion=
Ux X V
What substances net reabsorption
Glucose
Sodium
Urea
What substances net secretion
PAH
Creatine
What substnaces have excretion = filtration
Inulin
Mannitol
Net transport rate=
Filtered load - Excretion rate
(GFR X Px) - (Ux X V)
Clearnace of x=
(Ux X V)/Px
Proximal Renal Tubular Acidosis (Type 2) is due to
A diminished capacity of the proximal tubule to reabsorb bicarbonate
Distal Renal Tubular Acidosis (Type 1) is due to
Inability of the distal nephron to secrete and excrete fixed acids
