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Physio > Renal > Flashcards

Renal Flashcards

1
Q

Nephron with glomeruli located in

A

Outer cortex of kidney

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2
Q

Exretion rate (ER) =

A

(filtration rate - reabsorption rate) + secretion rate

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3
Q

Essential HT increases renal artery P leading to

A

Vasoconstriction of afferent

Vasodilation of efferent

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4
Q

Constriction of efferent a causes

A

Increase Glomerular Cap P

Decrease Peritubular Cap P

Decrease Nephron Plasma flow

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5
Q

Dilation of efferent A causes

A

Decrease Glomerular Cap P

Increase Peritubular Cap P

Increase Nephron Plasma Flow

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6
Q

Constriction of afferent A causes

A

Decrease Glomerular Cap P

Decrease Peritubular Cap P

Decrease Nephron Plasma flow

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7
Q

Dilation of afferent A causes

A

Increase Glomerular Cap P

Increase Peritubular Cap P

Increase Nephron Plasma flow

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8
Q

Normal GFR is

A

120 mL/min

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9
Q

Normal RPF is

A

600 mL/min

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10
Q

Filtration Fraction (FF)=

A

GFR/RPF

120/600

.20 or 20%

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11
Q

The greater FF the…

A

The higher the oncotic pressure in the peritubular capillaries

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12
Q

Afferent contriction affect on GFR, RPF, FF, and Glomerular filtration pressure

A
  • GFR: Decrease
  • RPF: Decrease
  • FF: Normal
  • glomerular filtration P: Decrease
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13
Q

Efferent constriction affect on GFR, RPF, FF, and Glomerular Filtration P

A
  • GFR: Increase
  • RPF: Decrease
  • FF: Increase
  • Glomerular Filtration P: Increase
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14
Q

Affect of Angtiotensin 2 on arterioles

A

Constricts both afferent and efferent but has a bigger effect on efferent

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15
Q

What are the consequences of Angiotensin 2

A
  1. Decrease RPF
  2. Increase GFR
  3. Increase FF
  4. Increase forces promoting reabsorption in the peritubular capillaries
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16
Q

Filtered load=

A

GFR X Px

17
Q

Excretion=

A

Ux X V

18
Q

What substances net reabsorption

A

Glucose

Sodium

Urea

19
Q

What substances net secretion

A

PAH

Creatine

20
Q

What substnaces have excretion = filtration

A

Inulin

Mannitol

21
Q

Net transport rate=

A

Filtered load - Excretion rate

(GFR X Px) - (Ux X V)

22
Q

Clearnace of x=

A

(Ux X V)/Px

23
Q

Proximal Renal Tubular Acidosis (Type 2) is due to

A

A diminished capacity of the proximal tubule to reabsorb bicarbonate

24
Q

Distal Renal Tubular Acidosis (Type 1) is due to

A

Inability of the distal nephron to secrete and excrete fixed acids

25
Q

Affect of acidosis on K

A

Shits K from the ICF to ECF

Decreased intracellular K reduces the K gradient causing a decreas in K secretion

26
Q

What causes prerenal ARF

A

Things that decrease renal perfusion pressure:

  1. Hypovolumia of hemorrhage
  2. Diarrhea
  3. Vomiting
  4. CHF

Physio (11 decks)

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