Resp Session 1 Flashcards
What is inspiratory reserve volume?
Additional volume that can be breathe in over that at rest
What is expiratory reserve volume?
Additional volume that can be breathed out at rest
What is partial pressure?
The fraction of total air pressure exerted by each gas
What is the partial pressure of gas proportional to?
Volume of the gas in the mixture
What is the partial pressure of oxygen in air at atmospheric pressure?
21.1 kPa
What does Boyle’s law state?
Pressure of a gas is inversely proportional to its volume of the temperature and amount of gas remain constant
Why does air become less dense as altitude increases?
Fewer molecules pressing down therefore molecules are more widely dispersed
What does Charles’s law state?
Is volume and amount of gas present is constant pressure is proportional to absolute temperature
What is saturated vapour pressure?
Pressure exerted by water molecules as they enter and leave the gas phase as in gas exchange at mucosal surfaces
What does saturated vapour pressure exclusively depend on?
Pressure
What is saturated vapour pressure at 37 degrees Celsius?
6.28 kPa
Why is air saturated with water vapour as it passes the URT?
To reduce the risk of damage to the LRT?
What causes The Bends?
Swimming up to the water surface too quickly so partial pressure changes are not gradual resulting in gas exchange which is not quick enough –> nitrogen bubbles
Describe the movement of gas molecules with relation to a liquid for example in gas exchange at a mucosal surface.
Gas molecules move in and out until an eqm of tension exerted by the gas in the liquid = partial pressure of gas in air
What can we assume about the gas tension of oxygen in arterial plasma?
It is equal to the partial pressure of oxygen in air assuming exchange time is sufficient
How is the amount of a gas dissolved in a liquid calculated?
Solubility x tension
What does using the tension of a gas dissolved in a liquid take into account when calculating how much gas is presentation?
any reaction that takes place so calculates the total content of reacted and dissolved gas
What components of oxygen transport need to be considered when considering the amount of oxygen dissolved in blood?
Fraction dissolved in plasma + fraction reacted with Hb
Why does the pulmonary circulation form basically no tissue fluid?
Low resistance
Low pressure
Receives whole cardiac output
Ventilation/perfusion ratio
Lost the airways in the lungs from largest to smallest.
Trachea –> bronchi –> bronchioles –> terminal bronchioles –> respiratory bronchioles –> alveolar ducts –> alveolar sacs
In which airways does gas exchange take place?
Respiratory bronchioles
Alveolar ducts
Alveolar sacs
Describe the blood supply to the airway tree.
Similar structure with bronchial arteries supplying bronchi themselves
What is tidal volume?
Volume breathed in and out with each breath during quiet respiration at rest
What are conducting airways?
Larger airways where gas exchange does not take place
Which airways are the last of the conducting airways?
Terminal bronchioles
Where do mucous membranes line in the respiratory tract?
Conducting portion
Are the number of mucus secreting cells in the mucus membranes constant throughout the respiratory system?
No
Where do serous membranes line the respiratory tract?
Pleural sacs which envelope each lung
Why does the lung appear ‘shiny’ on examination?
Covered by moist visceral pleura
What are Clara cells?
Domed cells without cilia that secrete lipoprotein surfactant and CC16 (Clara cell protein 16)
What does raised CC16 in serum indicate?
Leakage across air-blood barrier
What is the function of the lipoprotein surfactant secreted by Clara cells?
Prevents bronchiole collapse
What epithelium lines from the nasal cavity to the largest bronchioles?
Pseudostratified columnar with cilia and goblet cells
What epithelium lines the bronchioles to respiratory bronchioles?
Simple columnar with cilia and Clara cells
What epithelium lines respiratory bronchioles to alveolar ducts?
Simple cuboidal with Clara cells and a few sparse cilia
What type of cells are found in the alveoli?
Type I and II pneumocytes
What pushes odorons away from the olfactory regions of the respiratory tract?
Bauman’s glands
Describe the epithelium in the olfactory regions of the respiratory tract.
Thick pseudostratified columnar (particularly tall)with microvilli and no goblet cells
LP blends with submucosa
Where are the olfactory regions of the respiratory tract found?
Posterior and superior region of each nasal fossa
What maintains patency of non-olfactory regions in the nasal cavities?
Surrounding cartilage and bone