Resp Pharmcokinetic

Question 1

Time Constant Defined

Answer 1

Volatile anesthetic:
Time constant: is volume / flow
- Takes 3 time constant for 95% of a concentration change to be achieved

Circuit: Vol of Circuit/Fresh gas flow rate
Lung: Vol of lung divided by minute vent

Question 2

B2 Pathway to Bronchodilation

Answer 2

B2 -> G protein -> cAMP -> Decrease Intracell Ca -> sm relaxation

Question 3

Treatment of methemogloinemia and exception

Answer 3

Methylene Blue (1-2 mg/kg) ; but not in G6PD, can use Vit C

Question 4

Mepolizumab MOA

Answer 4

prevent eosinophil action by blocking interleukin-5.

Question 5

omalizumab MOA

Answer 5

Anti-IgE antibody

Question 6

Montelukast MOA

Answer 6

Leukotriene Modifier