Resp Lecture 3 ๐๐จ๐ฌ Flashcards
Definition of Respiration
- To extract oxygen from the air and together with the cardiovascular system transport it to respiring tissues
- Remove carbon dioxide from respiring tissues(an end product of aerobic metabolism) and exhaust into atmosphere
INCREASE in:
Size
And
Distance
Metabolic Rate
phrenic motor nucleus (C3-C5)
phrenic nerve (diaphragm)
intercostal motor neurones (T1-L1)
internal & external intercostal nerves
abdominal motor neurones (T7-L1)
abdominal nerve (rectus abdominus)
70% of inspiratory effort is produced by
diaphragm contraction
INSPIRATION
ACTIVE PROCESS)
Ribs move up and out
Diaphragm flattens
EXPIRATION
EXPIRATION
(PASSIVE PROCESS AT REST)
Ribs move down and in
Diaphragm doms up
Internal intercostal
Expiration
External intercostal
Inspiration
Diaphragm
INSPIRATION
Ppul
Pulmonary
Ppl
Pleural Pressure
Pneumothorax
Thoracic puncture wound โข Air rushes into chest โข Loss of negative pleural pressure
Vitalographs
Measure Gas Volume Dynamics
Respiratory Muscles and their nervous innervation The main respiratory muscles include the diaphragm and
external intercostal muscles (used for inspiration) and internal intercostals and abdominal muscles (for active expiration during exercise but also for cough and vocalization).
At rest, inspiration is an active process requiring muscle contraction whereas expiration is
passive relying on the recoil forces of the chest wall & lungs.
The lungs are separated from the chest wall by the
pleural space
Measurements of pressure within the pleural space (intrapleural pressure; Ppl) indicate a
pressure gradient such that the intrapleural pressure is negative (-2 to -10 cm water) relative to the alveolar or pulmonary pressure (intrapulmonary pressure; Ppul)
This negative Ppl helps keep the lungs from
collapsing and โadheresโ them to the chest wall.
During an inspiration chest volume increases The net efect is a more negative pleural pressure which causes
the lungs to expand with the chest. The result of the lungs inlating is a decrease in pulmonary pressure relative to atmospheric pressure. Since air moves from areas of high to low pressure, air rushes into lungs.
The volume of air moving into the lungs at rest is the
tidal volume
VT which is 0.5 L for an
average adult human. This can be measured on a spirometer.
The volume of air from a maximal expiration to maximal inspiration
vital capacity.
Residual volume cannot be
measured with a spirometer but assessed by a dilution method involving breathing helium gas (which is inert). This techniques allows total lung capacity (TLC) to be measured.
Volumes = measured;
capacities = calculated; Capacities = sum of two or more volumes
List of evolution of respiratory stuff
- ameba
-insect - cartilage fish
- lung fish
- amphibious
- reptiles
Increase in the size and distance and metabolic rate
Rictus abdominals
Is for active expiration only
Broken neck =
C3 and c5 no control over intercostal muscles = no breathing
Active expiration
Cough, laugh, physicals activity
Causation for dead space
Dis = 2.2ml x weight
Treatment for pneumothorax
Restoring negative ppl
Forced ventilation capacity
5L 80%