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Principles semester 2 > Resp. lab whiteboard > Flashcards

Resp. lab whiteboard Flashcards

1
Q

What PFT is effort dependent

A

FEV1

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2
Q

FEV1 normal

A

> 80% predicted

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3
Q

Volume of air that can be exhaled after max inhalation

A

FVC

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4
Q

Normal FeV1:FVC ratio

A

75-80%

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5
Q

FEV1/FVC restrictive disease

A

normal

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6
Q

FEV1/FVC in obstructive disease

what does it do and by how much

A

reduced <70%

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7
Q

Which PFT is useful in diagnosing obstructive vs restrictive disease

A

FEV1: FVC ratio

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8
Q

What PFT is most sensitive to small airway disease?

A

FEF 25-75%

mid max exp flow

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9
Q

FEF 25-75% in restrictive disease

A

normal

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10
Q

normal FEF 25-75%

A

100 + or - 25%

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11
Q

Maximum voluntary vent (MMV)

what is it, what are normal values

A

amount of air out on treadmill

Male: 140 - 180 L
Female: 80-120 L

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12
Q

DLCO is:

A

Volume of carbon monoxide that infuses through alveolar membrane

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13
Q

DLCO is based on

A

fick’s law of diffusion

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14
Q

Normal DLCO

A

17-25 mL/mn/mmHg

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15
Q

Brochodilator MOA

A

Beta 2 stimulation->increased cAMP–>decreased Ca2+

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16
Q

Anticholinergic MOA

A

M3 antagonism –> decreased IP3–>decreased Ca 2+

17
Q

Corticosteroid MOA

A

Stimulates intracellular steroid receptors

regulates inflammatory protein synthesis

18
Q

Cromolyn MOA

A

stabilizes mast cell membrane

decreases mediator release

19
Q

Leukotriene modifers MOA

A

inhibits s-lipogenase enzyme – > decreased leukotriene synthesis

20
Q

Methylxanthine MOA

A

inhibits phosphodiesterase –> increases cAMP–>increases endogenous catecholamine–>inhibits adenosine receptor

21
Q

Methylxanthine MOA

A

Inhibits phosphodiesterase–>increased cAMP–>increases endogenous catecholamines–>inhibits adenosine receptors

22
Q

FVC normal volumes

A

female:
Male: 4.8 L
Female: 3.7 L

22
Q
A
23
Q
A

Principles semester 2 (17 decks)

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