Neuro - anesthetic implications Flashcards
exam 1
Average CBF in adults
750 mL/min (15-20% of CO)
Rate of CSF production
15-20 mL/hr
total volume of CSF in system
150 mL
Spinal cord and brain blood supply
often have redundancy
Only artery of spinal chord that is not redundant
Artery of Adamkiewicz (Enters SC at T7 and suplies lumbosacral section)
SCPP level recomendations
> 40
Most important extrinsic factor influencing autoregulation
Key regulator or CBF
PaCO2
Intracranial HTN
sustained ICP 20-25 mmHg or higher
*some texts say 15 mmHg
Nitrous with neuro?
NO
Volatiles and neuro
give 0.5 MAC because all volatiles interfere with autoregulation
Ketamine a vasoconstrictor/vasodilator?
vasodilator and should be avoided
Circulatory steal phenomenon
arterioles in ischemic areas are maximally dilated and will not respond to vasodilators
so other vessels vasodilate and get blood instead
Fluid management: avoid
- dextrose
- hespan
- dextran
use NS
What agents are associated with isoelectric EEG changes?
- propofol
- isoflurane
- thiopental
Somatasensory evoked potentials (SSEP) monitors
ascending pathway (peripheral to brain)
tells us if there is an intact pathway from peripheral to spinal cord
SSEP anesthetic considerations
- Need goo mAP for good signals
- 0.5 MAC because SSEP is decreased with volatiles
*communicate what you give because monitoring is happening