resp 8 Flashcards
name the steps of CO2 removal that the lungs
the CO2 in the plasma goes into alveoi
HbCO2 —> Hb + CO2 (then leaves the blood cell and goes into alveoli)
exchanger reverses so HCO3- can go back to CO2 and go into alveoli
what is our current model for understanding control of respiration?
- medulla controls inspire and expire muscles
- Pons give sesory info and interact with medulla neurons which influences ventillation
- rythmic breathing unconsious comes from neurons in the brainstem
- modulated by chemo&mechano receptors in higher-brain centers
which control bundles are in the medulla?
DRG and VRG
which control bundles are in the Pons?
PRG
what does the DRG do? and what does the coat NTS do?
controls inspiratory muscles via phrenic nerve and intercostal nerve
NTS receives input from the peripheral mechano and chemoreceptors
what does PRG do?
receives sensory information from the DRG to coordinate a smooth muscle rythm
what does VRG do?
has a region called the PRE-BOTZINGER COMPLEX which has pacemakers that initiate respiration
control muscles but typically remian quiet
-keeps upper airways open (can cause snoring)
is neuronal ramping a feedback loop? yes or no, why?
yes. during inspiration, neuron activity steadily increases. at the end of inspiration, it suddenly shuts off.
how do glomus cells know when O2 is low?
ATP sensitive K+ channel
open when normal O2
closed when less O2 which depolarizes Glomus cell and releases Ach which sends signal to medulla
peripheral chemoreceptor
what do the central chemoreceptors do? (in spine)
provides continous intput to control center and is sensitve to H+
respond to H+ (the ones that are converted from CO2) cuz H+ cannot cross the barrier