Residue surveillance

Question 1

What is the purpose of residue surveillance?

Answer 1

monitor levels of compliance
take corrective action when regular violations or trends occur

Question 2

Why do residues occur?

Answer 2

withdrawal periods not completed or inadequate
higher dose or longer period of administration than authrorised
illegal or unauthorised drugs used

Question 3

Who is responsible for residue surveillance in the UK

Answer 3

Veterinary medicines directorate (VMD)
Veterinary residues committee (VRC)
FSA

Question 4

What is a maximum residue limit (MRL)

Answer 4

the max conc of a residue that is legally permitted in or on a food - ensures the ADI is not exceeded

Question 5

What is acceptable daily intake (ADI)

Answer 5

an estimate of the amount of a substance (on a bodyweight basis) that can be ingested over a lifetime without risk to the consumer

Question 6

What is the purpose of a withdrawal period?

Answer 6

to allow enough time to be sure any residues in edible tissues have depleted below the MRL

Question 7

How is an acceptable daily intake (ADI) calculated?

Answer 7

CVMP identify the quantity of residue that had no adverse effect - the ‘no observable adverse effect level’ (NOAEL)
This is divided by an uncertainty factor to allow for possible differences between individuals and data

Question 8

What is therisk of antibiotic residues

Answer 8

allergy
bacterial resistance
starter cultures in yoghurt and cheese production

Question 9

What is the calculation for the concentration of antimicrobial in a cows milk

Answer 9