Research Studies Flashcards

1
Q

IRB Exemption

A

-chair gives exemptions
-pose little risk
-does not involve a sensitive topic or population
-educational

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2
Q

IRB Expedited

A

-subset of board reviews it
-minimal risk (surveys, healthhy pops, non invasive, existing data)
-no interventions

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3
Q

IRB Full

A

-entire board reviews
-more than minimal risk
-sensitive topic or populations
-any research with an intervention

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4
Q

IRB Application Contents

A

-additional questions about study plans
-informed consent
-apropriate management of data

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5
Q

Informed Consent

A

-informed
-can opt out
-lay language (6th grade)
-answet questions
-contact info
-sign
-voluntary

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6
Q

Evidence Based Practice

A

integration of:
-evidence
-clinical expertise
-patient values

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7
Q

PubMed

A

-access to medline
-best source for RCT

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8
Q

Medline

A

-National library of medicine’s database

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9
Q

Primary Sources

A

-only clinical trials
-RCT, cohort, case control

-current but must read it all

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10
Q

Cochrane

A

-database for systematic reviews

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11
Q

Hierarchies of Evidence

A

-1a-5
-A-F

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12
Q

Systematic Reviews of RCT

A

-1a
-review or meta analysis of RCT

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13
Q

Randomized Control Trials

A

-1b
-group randomized into experiemental groups
-narrow confidence interval

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14
Q

All or None

A

-1c
-all Pt died before but some lived after
-some pt died before but none died after

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15
Q

Systematic Review of Cohort Studies

A

-2a
-review or meta analysis of cohort studies

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16
Q

Cohort Studies

A

-2b
-already in a group and compare different treatments

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17
Q

Outcomes Research

A

-2c
-how much value does it give to the pt
-not experimental

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18
Q

Systematic Review of Case Control

A

-3a
-review or meta analysis of Case control studies

19
Q

Case Control Studies

A

-3b
-find people with outcome and control that dont have outcome
-look back in time to find possible causes

20
Q

Case Study or Series

A

-4
-detailed analysis of cases

21
Q

Bench Research

A

-5
-non human research

22
Q

Expert Opinion

A

-5

23
Q

Grades

A

A-F
A: strong evidence, level 1 study
F: expert opinion

24
Q

PEDro

A

-tool to measure the quality of RCT
-0-10, 6 being good

25
Q

Quadras

A

-measure the quality of a study that investigattes accuracy of a test) outcome meausure
0-14, 7 being good

26
Q

Introduction

A

-purpose statement
-what is the problem
-why is it important
-what is the purpose

27
Q

Hypopthesis

A

Null: no different between x and y
Alternative: there will be a difference between x an y

-can reject or fail to reject your null

28
Q

Methods

A

-Participants: why and who, when, how

-Instrumentation: validity, outcome measures, interventions

-Procedures: must be reproducible

-Data Analysis: explain how the data was handled

29
Q

Results

A

-Outcomes of analysis
-tables and graphs
-no interpretation of data

30
Q

Discussion

A

-compared to previous literature
-implications
-strengths of the study
-limitations
-interpretations

31
Q

Conclusion

A

-overview of study
-overview of findings

32
Q

Meta Analysis

A

-systemic review with calculations of each study
-forest plot

33
Q

Order of Parts of a Study

A

Abstract
Intro
Methods: participants
Methods: instrumentation
Methods: procedures
Methods: data analysis
Results
Discussion
Conclusion

34
Q

Descriptive Studies

A

-Retrospective
-Normative
-qualitative

-describes data

35
Q

Exploratory Studies

A

-correlational: relationships
-predictive: reliability and validity
-case control and cohort (quasi experimental)

36
Q

Experimental Studies

A

-RCT only true
-cause and effect

37
Q

One-Way Repeated Research Design

A

-one group doing the same thing over titme

38
Q

Posttest-Only Randomized Group

A

-randomized
-2 or more groups that are only measured after the intervention

39
Q

Posttest-Only Non-Randomized Research Design

A

-non randomized
-2 or more groups that are only measured after the intervention

40
Q

Factorial-Fully Independent Research Design

A

-2+ interventions at the same time
-each person stays in the same group the whole time

41
Q

Factorial-Fully Repeated Research Design

A

-2+ interventions at the same time
-all participants switch groups throughout the study

42
Q

Factorial Mixed/Split Plot Research Design

A

-with or without randomization
-Multiple interventions (independent groups) move through time
-one intervention vs another; pre post post 2
-most common in PT

43
Q

Crossover Research Design

A

-with or without randomization
-groups switch interventions after 1st is done