Reproductive System Flashcards

1
Q

What are the ovaries?

A

Where the egg is produced in the process of oogenesis. The outer layer of the ovaries produces primary oocytes and follicle cells surrounding it called a primary follicle. Follicle cells form a wall many cells thick and fluid collects inside it to make a Graafian follicle. The mature follicle forms a blister on the surface of the oocyte is released. After puberty one primary follicle develops a month.

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2
Q

What are the oviducts?

A

Extends from the ovaries to the uterus. They are fringed with fimbriae. The lining of them is ciliated
and muscular and the movements of the cilia and the muscles move the oocyte towards the uterus. Fertilisation takes place in the Fallopian tubes.

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3
Q

What is the uterus?

A

Where the fertilised egg develops. It has the endometrium, inner layer rich in blood vessels, and the myometrium, the middle layer composed of smooth muscle. The endometrium builds a lining periodically which is shed if no fertilisation occurs. The function is to carry the foetus through pregnancy.

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4
Q

What is the cervix?

A

The lower portion of the uterus which forms the neck of the uterus and opens into the vagina. The narrow opening of the cervix is called the os which allows menstrual blood to flow out. During pregnancy it closes to keep the foetus in. It also dilates during labour to allow the foetus out. It is covered by epithelium (squamous or columnar).

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5
Q

What is the vagina?

A

A muscular tube containing elastic tissue and a folded lining so it can enlarge. It is the birth canal. The epithelium lining the vagina secretes an acidic fluid preventing the growth of harmful organisms.

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6
Q

What are the testes?

A

Composed or many seminiferous tubules which are tightly coiled tubes where spermatogenesis occurs. It takes place fro the outer layer of tubules, the germinal epithelium, towards the centre of the tube where sperm break away and move to the epididymis. Between the tubules are connective tissue, blood vessels and instertitial cells/cells of Leydig which secrete testosterone. Testosterone enters the seminiferous tubules in the testes and stimulates cells associated with spermatogenesis.

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7
Q

What is the epididymis?

A

Coiled tube at the posterior of the testis. It’s function is storage, maturation and transport of sperm. It connect the ducts of the testis to the vas deferens. Some fluid is reabsorbed making sperm more concentrate. The sperm become mobile here.

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8
Q

What is the prostate gland?

A

A compound wrapped around the urethra and placed just below the bladder, secreting alkaline fluid to neutralise the acidity of the vagina, forming parts of the seminal fluid.

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9
Q

What are the seminal vesicles?

A

Glands formed as pockets in the walls of the vas deferens. The fluid in the seminal vesicles is the seminal fluid which is alkaline and contains proteins, enzymes, fructose for energy and mucus.

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10
Q

What is the vas deferens?

A

Tubes carrying sperm from the testis to the urethra. Each tube has smooth muscle which contracts to move sperm forward.

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11
Q

What is the urethra?

A

Runs from the bladder to the end of the penis. Carries urine and sperm out.

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12
Q

What is the penis?

A

Has an internal structure of erectile tissue composed of a number of blood spaces separated by sheets of connective tissue. The penis contains the urethra. It introduces semen into the vagina and is the route of urine.

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13
Q

What does FSH and LH do?

A
FSH = made by the pituitary gland, stimulates follicle growth 
LH = produces by the pituitary gland and causes ovulation
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14
Q

What does oestrogen and progesterone do?

A

Oestrogen is produced by follicle cells and causes a build up of endometrium.
Progesterone is produced by the corpus luteum and maintains the endometrium.

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15
Q

Describe the menstrual cycle.

A

FSH causes an egg and follicle to mature - oestrogen is released - oestrogen inhibits FSH and builds up the endometrium making it more vascular - stimulates LH - causes ovulation - leaves the Graafian follicle which degenerates into the corpus luteum - releases progesterone - maintains the endometrium - if no egg is fertilised the CL breaks down and progesterone stops - endometrium breaks down.

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16
Q

Describe fertilisation.

A

Sperm are deposited at the top of the vagina near the cervix (most leak out). The cervix is blocked by mucus and this is only thin enough to allow the passage of sperm during the first part of the menstrual cycle. The movement of the sperm to the oviducts are due to the tails and the cilia of the tubes. Fertilisation takes place in the oviducts. Many sperm surround the ovum and penetrate the outer layers which are made of follicle cells. Sperm must undergo the acrosome reaction to get into the egg where enzymes are released, allowing the sperm in. The sperm nucleus and the ovum nucleus fuse.

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17
Q

Describe pregnancy.

A

The fertilised ovum moves down the oviduct and divides into a morula. It then forms a hollow ball of cells called the blastocyst, and the cells around it divide into the inner cell mass (becomes the baby) and the trophoblast (becomes the placenta). The trophoblast secreted HCG which can be detected in urine. The placenta is the organ of exchange - oxygen and nutrients pass across to the baby and CO2 and waste products pass back into maternal circulation. Some antibodies also cross the placenta. The period of fertilisation to birth is gestation.

18
Q

What is the foetus like at 1 month old?

A

The embryo has the beginnings of a gut, kidneys and brain and the heart beats.

19
Q

What is the baby like at 2 months old?

A

Bone, muscle and cartilage begin to round out the contours of the body and sex organs form. The face and neck develop.

20
Q

What is the baby like at 12 weeks?

A

Sex organs show the sex of the baby and the heart beat can be heard.

21
Q

What is the baby like at 16 weeks?

A

The heart and blood vessels are fully formed and the urinary system is functional.

22
Q

What is the baby like at 20 weeks?

A

The foetus can suck it’s thumb, yawn, stretch and make faces skin structures begin to attain final form, sweat and sebaceous glands are formed and hair and nails on fingers and toes form.

23
Q

Describe birth.

A

At 28 weeks the baby stands a good chance of surviving. Around the baby is the amniotic fluid in the amniotic sac which ruptures when the water breaks. Oxytocin is released by the pituitary gland causing contractions and contractions cause more oxytocin so a positive feedback mechanism occurs. The contractions cause the baby to be born + then the placenta is delivered

24
Q

What are the 9 reasons for infertility in males?

A
  1. Sperm disorders (most common) like not enough sperm, they don’t move fast enough or are the wrong shape
  2. Blockages in sperm carrying tubes due to eg vasectomy
  3. Injury to testicles
  4. Diseases like mumps
  5. Impotence
  6. Medical disorders like diabetes or high blood pressure
  7. Drugs like alcohol or nicotine
  8. Medications like antibiotics
  9. Radiation treatment
25
Q

What are the 12 causes of infertility in females?

A
  1. Ovaries not producing eggs
  2. Damage to oviducts due to infection like chlamydia
  3. Endometriosis
  4. Polycystic ovary syndrome
  5. Premature ovarian failure
  6. Conditions like diabetes or cancer
  7. Fibroids
  8. Smoking
  9. Drinking
  10. Being overweight
  11. Being underweight
  12. Stress
26
Q

What is endometriosis?

A

Tissue similar to the lining of the womb develops in other places as well, such as the oviducts or ovaries.

27
Q

What is polycystic ovary syndrome?

A

Hormonal imbalance in the ovaries causes change in the menstrual cycle and ovulation stops.

28
Q

What is premature ovarian failure?

A

Ovaries don’t produce eggs regularly

29
Q

What are fibroids?

A

Non-cancerous growths on the wall of the womb.

30
Q

What is an ectopic pregnancy?

A

The egg implants in the wrong place such as oviducts, ovaries, cervix or abdomen. They cause pain and unusual bleeding and if the oviducts rupture there may cause serious internal bleeding. Usually occurs because the oviducts have been damaged in an earlier operation or pelvic inflammatory disease from an untreated STI. If the oviducts have been damaged they may become inflamed or scarred so the egg can’t pass to the womb.

31
Q

How can a blood test diagnose infertility?

A

A blood sample can show any hormonal imbalances. This could show the cause of infertility and impotence and can diagnose ectopic pregnancies.

32
Q

How can sperm analysis diagnose infertility?

A

A sample of semen is taken to the clinic for testing. They examine the numbers of sperm, how they move and whether they have normal structure.

33
Q

How can an ultrasound diagnose infertility?

A

It is easy to perform and safer than X-rays. It uses high frequency sound waves from a transducer that is moved over the abdomen. The sound waves bounce off soft tissue and fluid filled organs and the echoes are converted into images. An infertility ultrasound can verify that the uterus and ovaries are present and if any abnormalities are there.

34
Q

How can a hystero-salpingogram diagnose infertility?

A

It is a radiology procedure. The radiographic contrast (dye) is injected into the uterine cavity through the vagina and cervix. The uterine cavity fills with dye and if the oviducts are open the dye fills the tube and spills into the abdominal cavity. This determines if they are open or blocked and where the blockage is.

35
Q

How can a laparoscopy diagnose infertility?

A

It is a surgical procedure allowing surgeons to access inside of the abdomen and pelvis without making large incisions. A laparoscope is a small tune with a light source and camera which relays images of the inside of the abdomen to a monitor. A biopsy can also be done. This is useful in visually studying any condition affecting the female reproductive system

36
Q

What are some fertility treatments to treat infertility?

A
  • medicine such as Clomid for women stimulates the ovaries to produce eggs.
  • many treatments for men helping improve quality of sperm or help it reach the womb
  • testosterone medication
  • surgery to remove epididymis blocks
  • ICSI
37
Q

What is ICSI?

A

Intracytoplasmic sperm injection - a fertility treatment. It is similar to IVF. A single sperm is injected into an egg in a lab and the resulting embryo is transferred to the womb. This means that as long as a small amount of sperm can be obtained it is possible to fertilise the egg. This is used after a vasectomy or when the problem is between the sperm and the egg preventing fertilisation.

38
Q

How can IVF treat infertility?

A

Eggs are removed and mixed w sperm in a lab. When they’ve been fertilised they’re transferred to the womb. The woman takes medication to control the timing of her monthly cycle so eggs can be removed on specific days. With this method several eggs mature at once which is called super ovulation. Usually the eggs are collected during an ultrasound by a thin needle passing through the vagina into the ovary, and sperm is collected through a sample. The sperm are washed and spun at high speed so the healthiest are chosen. They are then mixed together. Successful fertilisation can be seen w a microscope after 16-20 hours.

39
Q

What are some rules of IVF?

A

Can use your own or donors sperm and eggs
Embryos and sperm can be frozen but there are strict legal rules
Women under 40= 2 embryos transferred using a soft plastic tube
Women over 40 = 3 embryos

40
Q

What are side effects and implications of IVF?

A

Headaches
Mood swings
Increased chance of multiple pregnancies which has risks like miscarriage, early labour and health problems in pregnancy such as high blood pressure.

41
Q

How can sperm donation treat infertility?

A

Males who can’t produce sperm can’t become fathers other than by adoption or through artificial insemination by a donor (AID). The anonymous donors semen is screened for microorganisms and a careful medical history is taken to ensure there is good health and free from as many physical / mental disorders as possible.

42
Q

How can lifestyle changes treat Infertility?

A
Stopping smoking
No alcohol
Avoiding stress
Keeping testes cool 
Wear loose clothing