Cardiovascular System Flashcards
What are the 9 parts of the heart?
- Superior vena cava
- Inferior vena cava
- Right atrium
- Right ventricle
- Pulmonary artery
- Pulmonary vein
- Left atrium
- Left ventricle
- Aorta
What are the 4 valves in the heart and where are they?
- Tricuspid valve = right side of the heart between the atria and ventricles
- Bicuspid valve = left side of the heart between atria and ventricles
- Semilunar valve on the left
- Semilunar valve on the right - between ventricles and arteries.
What is cardiac muscle?
Makes up the heart, specialised tissue that allows the heart to contract in an organised manner to pump blood to the lungs and tissues.
What is the septum, bundle of His and purkinje fibres?
The septum is the muscle running between the two ventricles. The bundle of His are located through the septum, and divide at the apex into branches of Purkinje fibres, up the walls of the heart.
What is the function of valves?
Prevent the backflow of blood.
What is the ‘lubb-dupp’ sound of the heart?
The lubb is the atrioventricular valves closing and the dupp is the semilunar valves opening.
Describe the flow of blood.
Heart (aorta) - arteries - arterioles - capillaries - venules - veins - vena cava - heart
Give the main properties of arteries.
- Thick elastic walls to withstand high pressures
- They expand and recoil
- Blood flows away from the heart
- Blood is at high pressure
- High oxygen content
Describe the structure of an artery.
Tunica externa is the outer layer made of collagen fibres.
Tunica media is thicker, made of smooth muscle cells and elastic fibres
Tunica intima is made of endothelium that lines the lumen
The lumen is the hole in the middle
What happened when coronary arteries become blocked?
Partially blocked = when exercising angina occurs
Fully blocked = no blood reaches the heart so no oxygen gets to it so a heart attack occurs and part of the heart dies
Give the main properties of the capillaries.
- One cell thick for short diffusion pathway
- Gas exchange occurs
- Permeable to allow diffusion of gases
Give the main properties of veins.
- Veins have a much wider lumen to keep blood flowing
- Blood flows to the heart
- Have valves
- Blood kept in the veins by contraction of muscle around them
- Walls much thinner than arteries
- Blood pressure lower
- Low oxygen content
What is blood made of?
Plasma, red blood cells (erythrocytes), white blood cells (leukocytes) and platelets (thrombocytes).
What are the main functions of the blood?
- Transport of substances
- Temperature regulation
- Defence against disease through thrombocytes
- Reproduction
Describe the main properties of red blood cells/ erythrocytes (6).
- Contain haemoglobin, an iron rich protein which picks up oxygen in the lungs and transports it to tissues, gives the cells the red colour
- Carries oxygen
- Structured like bi-concave with no nucleus and are created in red bone marrow of large bones
- Circulate for 120 days
- Anaemia = too few red blood cells or not enough haemoglobin because of too little iron
- Carbon monoxide binds to haemoglobin, taking it to tissues
Describe the main properties of white blood cells/leukocytes. (5)
- 5 major types
- Fight infection which is why WBC count indicates infection
- Also created in bone marrow
- Granulocytes such as monocytes/neutrophils which combat infection by engulfing cells and cell debris
- Lymphocytes such as T cells or B cells - T cells attack a virus infected/cancer cell, B cells produce antibodies which bind bacteria and destroy them.
Describe the main properties of platelets / thrombocytes. (5)
- Responsible for blood clotting
- Small with no nucleus
- React to various clotting factors in plasma
- Formed in bone marrow
- Blood clotting is vital, preventing excess blood loss from damaged blood vessels and preventing pathogen entry.
Describe the cardiac cycle.
Deoxygenated blood from body - vena cava - right atrium - tricuspid valve - right ventricle - semilunar valve - pulmonary artery - lungs - oxygenated blood - pulmonary vein - left atrium - bicuspid valve - left ventricle - semilunar valve - aorta - body.
Define myogenic.
The heart is describe as myogenic because it can contract without stimulation from the nervous system or hormones.
Describe the control of the heart beat.
- Electrical signal from group of cells at the top of the right atrium called sino atrial node (pace maker)
- Atria contract simultaneously - blood pushed into ventricles
- Electrical signal stops for a moment at the Atrio ventricular node so the atria empties
- AVN passes signal down bundle of His to the apex of the heart
- Then signal spreads up purkinje fibres causing ventricles to contract - blood is pushed out of the heart