Digestive System Flashcards

1
Q

What is the oral/buccal cavity?

A

Mouth. This is where salivary glands secrete saliva with digestive enzymes like amylase in to digest starch to maltose. The teeth grind food into smaller pieces and the tongue mixes it with saliva to form a bolus - mechanical digestion.

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2
Q

What is the oesophagus?

A

Behind the trachea connecting mouth to stomach. When you swallow a piece of cartilage called the epiglottis covers the trachea so it doesn’t go down the windpipe. The bolus moves down it by gravity and peristalsis. A sphincter muscle at the bottom of the oesophagus opens up to let food into the stomach.

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3
Q

Define peristalsis.

A

Wave like contractions and relaxations of circular muscles to push food along.

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4
Q

What is the stomach?

A

Left side of the body under the diaphragm. A muscular, sac like organ that connects the oesophagus and small intestine. It chemically breaks down food. It has muscular walls that churn food and mix it with enzymes and mucus making chyme. The stomach wall has goblet cells secreting mucus, cells secreting HCL for acidic conditions for pepsin to work, and cells that secrete pepsin that breaks down proteins to amino acids. After 1-2 hours the sphincter opens and lets chyme into the duodenum.

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5
Q

What is the small intestine?

A

Has the duodenum, Jejunum and ileum. It digests proteins, lipids and carbohydrates with digestive enzymes - protease, lipase and amylase. It is pushed through by peristalsis and ingested food is absorbed across the villi. The small intestine receives bile from liver and enzymes in an alkaline juice from the pancreas. The alkaline neutralises HCL and bile breaks down large fat globules into smaller ones so lipase works.

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6
Q

What is the liver?

A

Stores glucose as glycogen and synthesis’s plasma proteins such as the blood clotting factor fibrinogen. Also produces bile which is stored in the gall bladder and flows into the duodenum along the bile duct. Bile doesn’t contain enzymes but breaks down large fat globules. This is emulsification and lets lipase works. It is to the right of the stomach.

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7
Q

What is the gall bladder?

A

Located under the liver and stores and releases bile via the bile duct into the duodenum.

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8
Q

What is the pancreas?

A

Feather shaped organ underneath the stomach. It produces pancreatic enzymes and digestive alkaline juices. It produces insulin, proteases like trypsinogen and lipase, amylase and Maltese. These go into the duodenum.

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9
Q

What is the large intestine?

A

Split into 3 parts; the caecum, colon and recriminations. Food is pushed through by peristalsis and remaining water is absorbed. It also absorbs vitamins from bacteria in the colon. It compacts farces and bacteria in large intestine and nutrients prevents pathogens from growing. It stores unusable food matter.

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10
Q

What is the rectum.

A

A chamber that ends in the Anus which temporarily stores undigested food.

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11
Q

Describe the process of digestion.

A

Buccal cavity and teeth mechanically digests food into a bolus and starch is slightly broken down from amylase in saliva. Bolus moves down oesophagus by gravity and peristalsis. It enters stomach through a sphincter where it is churned with hydrochloride acidic mucus and enzymes which breaks down proteins. It enters the small intestine (duodenum) through another sphincter and nutrients get absorbed by microvilli. Bile from the liver breaks down large fat globules and alkaline juices neutralises the HCL, and digestive enzymes break down proteins fats and sugars. It then goes through the jejunum and ileum into the large intestine. It moves through the caecum, then colon where water is reabsorbed and rectum which stores it.

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12
Q

Describe the absorption of food including the structure and function of gut villi.

A

Small intestine has villi. The villi has a lacteal or lymph vessel in the middle surrounded by a network of capillaries surrounded by epithelial cells. The villi increase the SA of the small intestine and microvilli from epithelial cells increase it further. Digestion in the SI breaks down food into fatty acids and glycerol, polypeptide and disaccharides. Then enzymes in the microvilli such as aminopeptidades, and disaccharidases like Maltase sucrose and lactase, break food down further. These components are absorbed in the capillary network and fatty acids and glycerol are absorbed into the lacteal.

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13
Q

What is a gastric ulcer?

A

Also known as a stomach ulcer, open sores that develop on the lining of the stomach. They can be gastric, duodenal or oesophageal.

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14
Q

What are the effects of gastric ulcers?

A

Weight loss bc pain from eating
Nutrients not absorbing properly so malabsorption and deficiency diseases
Pain in abdomen and back
Acid reflux where acidic contents of stomach come back through oesophagus
Vomiting
Vomiting blood from perforated ulcer.

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15
Q

How can diet cause a stomach ulcer?

A

Coffee as alcohol can cause an ulcer because they (especially mixed with nicotine) erode the mucous membrane of the stomach lining and increase the concentration of stomach Acid, so the acid damages the lining.

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16
Q

How can infection cause stomach ulcers?

A

Helicobacter Pylori (H.Pylori) is a bacterium causing stomach ulcers. it infects the stomach and causes gastritis (inflammation of the stomach lining) which leads to an ulcer forming. Severe complications include bleeding or perforated ulcers.

17
Q

How can NSAIDs cause a stomach ulcer?

A

Non steroidal anti inflammatory drugs prevent the stomach from producing protective mucus allowing the acid to harm the stomach lining. This is an issue for people who need to use NSAIDs eg people with arthritis.

18
Q

How can psychological causes cause a stomach ulcer?

A

Stress is a contributing factor. Could be because of a hectic lifestyle, physical trauma or emotional disturbance. It increases risk of them and lowers rate of healing of them.

19
Q

How can lifestyle cause stomach ulcers?

A

Smoking can cause stomach ulcers because mixed with alcohol it can erode the mucous membrane allowing acid to harm the stomach lining.

20
Q

How can a barium meal diagnose stomach ulcers?

A

Patients invest barium in a meal and X-rays show whether the ulcer is. This doesn’t show if the cause is H. pylori.

21
Q

How can an endoscopy diagnose an ulcer.

A

An endoscopy involves an endoscope which is a long, thin flexible tube containing a light source and camera. Images of the oesophagus and stomach can be seen. It is inserted trough the throat and the tip of the endoscope is guided into the stomach to look for ulcers, cancers and polyps. Instruments can be used to make a biopsy.

22
Q

How can a tissue biopsy diagnose a stomach ulcer?

A

Instrument on the endoscopes can take a biopsy which is a small sample of tissue and it can be examined to see if the cause is H Pylori so suitable treatments can be given.

23
Q

How can a blood test diagnose a stomach ulcer.

A

A small prick on the finger will take a small amount of blood to test for antibodies to the bacteria.

24
Q

How can medication treat a stomach ulcer?

A

If it is H. Pylori two or three antibiotics eliminate the infection. Common ones are amoxicillin, clarithromycin ad metronidazole. Also drugs like omeprazole are used to stop the stomach producing acid so the antibiotics can work and the ulcer can heal. Gastric ulcers by NSAIDs are treated in this way. the GP may recommend antacid medication for short term relief like Rennie.

25
Q

How can lifestyle changes treat stomach ulcer?

A

No food or drink that causes more severe symptoms like spicy food, alcohol and coffee. Not smoking also reduces the likelihood. No painkillers that are unnecessary for long periods of time.