reproductive function 2 Flashcards

1
Q

congenital disorders (male)

A

epispadia/hypospadia
cryptochidism

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2
Q

disorders of the testes and scrotum (male)

A

hydrocele, spermatocele, varicocele, torsion

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3
Q

cancers (male)

A

penile, prostate, testicular

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4
Q

sexually transmitted infections

A

chlamydia, gonorrhea, syphilis, herpes, trichomoniasis

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5
Q

spermatogenesis & male genital anatomy

A

generates and transports sperm
produces sex hormones
aids in urination
includes penis, scrotum, testes, duct system, & accessory glands

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6
Q

hypospadia (congenital penile variations)

A

-urethral meatus located on the ventral surface of the penis
-risk increases w maternal factors: age>35 yrs, obesity, use of fertility treatments, and hormone therapy
-most common penile variation

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7
Q

epispadia (congenital penile variations)

A

-urethral meatus occurs on the dorsal surface of the penis and may extend the entire length of the penis
-can cause urination problems
-increased risk of urinary tract infections
-usually develops during the 1st month of gestation; urinary defects often also present

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8
Q

cryptochidism (congenital penile variations)

A

-undescended testicle
-one or both testes do not descend from abdomen to scrotum;
-undescended testes usually remain along the path of descent

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9
Q

hydrocele (disorders of the testes) causes & diagnosis

A

-fluid accumulation btwn the layers of the tunica vaginalis or along the spermatic cord
-can affect one or both testes
-causes: congenital defect, inflammation, infection, trauma, and tumors
-diagnosis: painless scrotal enlargement that transilluminates and scrotal heaviness

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10
Q

varicocele (disorders of the testes)

A

-dilated vein in the spermatic cord
-results from valve issues that allow blood to pool in the veins
-most common cause for low sperm counts & decreased sperm quality bc of testicular ischemia
-more common in left testicle bc of anatomic factors

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11
Q

varicocele (disorders of the testes) causes & manifestations

A

-causes: congenital defects and obstructions
-manifestations: “bag of worms” feeling to the scrotum and scrotal heaviness

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12
Q

describe testicular torsion (disorders of the testes)

A

-abnorm rotation of the testes on the spermatic cord
-causes: trauma, but can also occur spontaneously
-manifestations: sudden scrotal edema & pain
-diagnosis: history, physical exam, & scrotal ultrasound
-treatment: manual manipulation & surgery

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13
Q

describe penile cancer

A

-rare malignancy
-the exact cause unknown
-risk factors: smegma, being uncircumcised, poor hygiene, phimosis, & HPV infections
-appears as a thick, grey-white lesion (Bowen lesion) or a red, shiny lesion (erythroplasia of Queyrat)
-risk factors: being uncircumcised, poor hygiene, phimosis, & HPV infections
-prognosis is good w early diagnosis & early diagnosis & treatment
-treatment: penectomy, chemotherapy, radiation, & surgical excision

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14
Q

describe testicular cancer

A

-uncommon but curable (even if metastatic) cancer most common in 15-35 year olds
-affecting one or both testicles
-risk factors: family history, infection, trauma, & cryptochidism
-manifestations: asymptomatic; a hard, painless, palpable mass that does not transilluminate; testicular discomfort or pain; enlargement of the testicle
-diagnosis: monthly self-testicular examinations
-treatment: orchiectomy, chemotherapy, & radiation

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15
Q

prostate cancer

A

-most common cancer in men
-slow-growing tumor w an unknown cause; as it grows, it obstructs urethra
-second leading cause of cancer deaths
-risk factors: history of STIs, fam history, high-fat diets, & androgen hormone replacement
-manifestations: urinary difficulties, erectile dysfunctions, blood semen, & hematuria
-diagnosis: biopsy, the prostate-specific antigen test, & prostatic acid phosphatase test
-treatment: radical prostatectomy, radiation, orchiectomy, & antitestosterone drugs
-for cancers diagnosed in early stage, active surveillance is appropriate

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16
Q

sexually transmitted infections

A

-infections that can be contracted through sexual contact
-more than 30 diff sexually transmissible bacteria, viruses, & parasites have been identified
-some can also be transmitted from mother to child during pregnancy & childbirth as well as through blood contact
-some of these are easily eradicated w appropriate treatment, whereas others remain for a lifetime
-3 are reportable to the Centers for Disease Control & Prevention – chlamydia, gonorrhea, & syphilis

17
Q

chlamydia

A

-chlamydia trachomatis: intracellular parasite that req a host cell to reproduce
-the most commonly reported STI in the US

18
Q

chlamydia complications & manifestations

A

complications: PID, epididymitis, prostatitis, infertility, & ectopic pregnancy, increases the risk for contracting other STIs
manifestations: if present, include dysuria; penile, vaginal, or rectal discharge; testicular tenderness or pain; rectal pain; & painful sexual intercourse

19
Q

gonorrhea

A

caused by Neisseria gonorrhoeae, an aerobic bacterium w many drug-resistant strains
-2nd most common STI

20
Q

gonorrhea complications & manifestations

A

complications: PID, epididymitis, prostatitis, infertility, ectopic pregnancy, arthritis, dermatitis, & endocarditis
manifestations: if present, include dysuria; penile, vaginal, or rectal discharge; redness/edema at urinary meatus (in men); testicular tenderness; rectal pain; painful intercourse; white blisters that darken & disappear

21
Q

syphilis

A

-ulcerative infection caused by Treponema pallidum, a spirochete that req a warm, moist environment to survive
-transmitted from skin or mucous membrane & from the mother to child through the placental barrier
-in utero, fetuses, are protected by Langhans layer for the first 4 months, so screening & treating the mother prior can decrease likelihood of fetus contracting the infection
-untreated may lead to fetal demise or defect affecting the bone, liver, lungs, & nerves

22
Q

Stage One: Primary Syphilis

A

-1+ painless chancres form at site 2-3 weeks after infection
-no other symptoms are present
-often go unnoticed & disappear abt 4-6 weeks later, even w out treatment
-bacteria become dormant
-contagious, but may not test pos, so testing should be repeated at a later date

23
Q

Stage 2: Secondary syphilis

A

-occurs abt 2-8 weeks after the 1st chancres form
-treatment in the primary stage can decrease the likelihood of developing this stage
-manifestations: generalized, brown-red rash; malaise; fever
-symptoms will go away without treatment, and again, the bacteria become dominant
-will test pos (if untreated) and is contagious, especially w direct contact w the rash

24
Q

Stage 3: Latent or tertiary syphilis

A

-begins when the secondary symptoms disappear and lasts 1-4 yrs
-can last for years; infection spreads to the brain, nervous system, heart, skin, and bones
-complications: blindness, paralysis, dementia, cardiovascular disease, and death
-will test pos (if untreated) & is only contagious during the early part of this stage

25
Herpes simplex virus (HSV) (viral STI)
-recurrent episodes of lesions, sores -transmitted through sexual, direct skin-to-skin contact, and from mother to fetus -risk of transmission is the greatest when lesions are present -the virus causes an initial infection at the entry site -then the virus travels along the nerve root where it remains dormant until the next outbreak, which will occur at the same site
26
HSV type 1
typically occurs above the waist and manifests as a cold sore
27
HSV type 2
typically occurs below the waist
28
genital herpes
outbreaks begin w a tingling or burning sensation at the site just before the lesion appears (prodrome) -the lesions first appear as a vesicle surrounded by erythema -vesicles rupture, leaving a painful ulcerative lesion with watery exudate -crust forms over the ulcer, and it heals spontaneously 3-4 weeks
29
genital herpes treatment
antiviral meds, avoiding reoccurrence triggers, proper hygiene, avoiding sexual act during outbreaks, and safe sex practices
30
human papillomaviruses (HPVs)
-benign growths on external genitals, cervix and anus caused by a group of viruses -incubation period can last up to 6 months; can lead to reproductive/anal cancer
31
HPV manifestations
asymptomatic; growths that can be raised, flat, rough, smooth, flesh-colored, white, grey, pink, cauliflower-like, large, or barely visible, w abnorm bleeding, discharge, & itching
32
HPVS diagnosis, prevention, & treatment
diagnosis: history, exam, Pap smear, biopsy, & PCR test prevention: vaccine & safe sex prac treatment: removal using chemicals, cryosurgery, electrocautery, laser therapy, or excision; treating sexual partners; & c section deliveries
33
Trichomoniasis
-caused by Trichomonas vaginalis (a parasite), a one-celled anaerobic organism that can burrow under the mucosal lining -in men, the organism primarily resides in the urethra & causes no symptoms -in women, the organism resides in the vagina -the organism cannot survive in the mouth or the rectum
34
Trichomoniasis complications, manifestations, diagnosis, & treatment
-complications: cervical cancer -manifestations: excessive odorous, frothy, white or yellow-green vaginal discharge; vagina & vulva irritation; itching painful intercourse; & dysuria -diagnosis: history, physical exam, & pap smear -treatment: antibiotic therapy, specifically metronidazole (flagyl), & screening & treating sexual partners
35
fetal sex determination
-female gonad (ovary) is default -male gonad (testis) only develops in the presence of SRY gene found on the 'sex determining region' of the Y chromosome
36
The type of sex chromosome complex established at fertilization of the oocyte determines...
the type of gonad that differentiates from the indifferent gonad
37
The type of gonad then determines the type of sexual differentiation that occurs....
in the genital ducts & external genitalia
38
Androgen Insensitivity
XY chromosome complex, but tissues do not respond to testosterone, Testis develop but do not descend, external genitalia does not form