Reproductive endocrinology

Question 1

What the earliest recognisable germ cell?

Answer 1

Primordial germ cell

Question 2

What does the presence of 2 polar bodies indicate?

Answer 2

Signifies sperm entry & completion of the second meitotic division

Question 3

What stimulates the pituitary to release LH/FSH?

Answer 3

GnRH from the hypothalamus

Question 4

Where do FSH & LH work?

Answer 4

The ovary

Question 5

What are the actions of FSH?

Answer 5

Thickens endometrium

Stimulate development of foliicles

Question 6

What are the 2 phases of the ovulation cycle?

Answer 6

Luteal phase

Follicular phase

Question 7

Before birth what is the oocyte surrounded by?

Answer 7

Granulosa cells

Question 8

How does oestrogen affect LH in the first 10 days?

Answer 8

Low levels inhibit LH

Question 9

How does oestrogen affect LH after the first 10 days?

Answer 9

High levels stimulate LH

Question 10

What triggers ovulation?.

Answer 10

LH surge

Question 11

What are the functions of oestrogen?

Answer 11

Stimulates bone & muscle growth
Stimulates endometriaal growth
Maintains female characteristics
Maintains glands

Question 12

What stimulates follicular gorwth?

Answer 12

FSH

Question 13

What is the corpus luteum?

Answer 13

Dead follicle

Question 14

Which hormone stimulates endometrial growth?

Answer 14

Progesterone

Question 15

Which hormone is released by maturing follicle?

Answer 15

Oestrogen

Question 16

Which 3 hormones are released by degenrating corpus luteum?

Answer 16

Oestrogen
Inhibin
Progesterone

Question 17

What does inhibin supress ?

Answer 17

FSH

Question 18

What does progesterone suppress?

Answer 18

GnRH

Question 19

What should be tested in a female presentation of infertility?

Answer 19

Pregnancy 
P21
Hormone profile
Chlamydia swab 
Rubella immunity