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AY Endocrine > Adrenal physiology > Flashcards

Adrenal physiology Flashcards

1
Q

What are the 3 layers of the adrenal cortex?

A

Zona Glomerulosa
Zona Fasiculata
Zona Reticularis

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2
Q

What is secreted from the Zona Glomerulosa?

A

Aldosterone

Mineralocorticoids

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3
Q

What is secreted from the Zona Fasiculata?

A

Cortisol

Glucocorticoids

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4
Q

What is secreted from the Zona Glomerulosa?

A

Sex steroids

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5
Q

What is released from the adrenal medulla?

A

Adrenaline

Noradrenaline

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6
Q

What stimulate cortisol release from the Zona Fasiculata?

A

ACTH from the anterior pituitary

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7
Q

What stimulates ACTH release from the pituitary?

A

CRH from the hypothalamus

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8
Q

Where are chromaffin cells found?

A

Adrenal medulla

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9
Q

What do chromaffin cells secrete?

A

Catecholamines

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10
Q

Where is angiotensinogen produced?

A

Liver

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11
Q

What converts angiotensinogen to angiotensin I?

A

Renin from the kidney

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12
Q

What converts angiotensin I to angiotensin II?

A

ACE from the lungs

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13
Q

What are the actions of angiotensin II?

A

Stimulate adrenal cortex to produce aldosterone
Increased thirst
Arterial vasoconstriction
Promote ADH secretion

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14
Q

What are the clinical appllications of corticosteroids?

A

Supress inflammation
Supress immune system
Replacement treatment

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15
Q

What are the 6 classes of steroid receptors?

A 
Glucocrticoid 
Mineralocorticoid 
Progeston 
Oestrogen 
Androgen 
Vitamin D
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16
Q

What is the action of cortisol on bones?

A

Accelerates osteoporosis
Decreases serum calcium
Decreases collagen formation
Decreases wound healing

17
Q

What is the action of cortisol or the circulatory & renal system?

A

Increases CO
Increases BP
Increases renal blood flow + GFR

18
Q

What effect does cortisol have on the immune system?

A

Decreaes capillary dilation/permeability
Decreases leucocyte migration
Decreases macrophage activity
Decreases inflammatory cytokine production

AY Endocrine (18 decks)

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