Reproductive Flashcards

1
Q

Estradiol

A

Most abundant sex hormone during reproductive years

Most potent

DIOLing up

Synthesized in ovaries only in reproductive years

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2
Q

Estrone

A

Synthesized in adipose

Weaker than estradiol

Predominant sex steroid after menopause

Exhausted ovaries looking to fat and saying ON YOUR OWN

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3
Q

Estriol

A

Pregnancy in massive quantities

Weaker than estradiol or estrone

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4
Q

Preg

A

All three increase estriol increase most

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5
Q

Estrogen receptor

A

Cytoplasm into nucleus

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6
Q

LH FHS

A

Increase estradiol which inhibits with neg feedback except surge

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7
Q

Estrogen effects

A

Development of female primary and secondary sex characteristics

Stimulate development of genitals, breasts, and follicles in ovaries
Thickening of vaginal wall

Increase vag lubrication
Stimulate growth of uterus and endometrial lining
Increase fat storage in female distribution

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8
Q

Bone estrogen

A

Close growth plate

Halt linear growth of bones

Girls-shorter bc start puberty earlier

Increase bone formation , decrease resorption why wome get osteoporosis after menopause

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9
Q

Estrogen blood

A

Increase transport proteins

Increase HDL

Decrease LDL

Why women hav lower CDV risk

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10
Q

Estrogen and progestin

A

Inhibit ovulation

Hormone replacement therapy

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11
Q

Progesterone

A

Steroid sex hormone

Produced in corpus luteum, placenta, adrenals and testes

In all hormone contraceptions

Pro-gestation(counteract rejection of foreign body)

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12
Q

Progesterone receptor

A

In cytoplasm, to nucleus where alter transcription

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13
Q

Effects progesterone

A

Nourish and protect pregnancy tissue

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14
Q

Progesterone and endometrial lining

A

Glandular secretionsincrease spiral artery formation (nutrients come in)

Inhibit contractions

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15
Q

Cervix progesterone

A

Increase production of thick cervical mucus

Protects pregnancy from infections

Prevent sperm to enter uterus (contraception

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16
Q

Progesterone and ER receptors

A

Decrease ER inc ells to put on hold and protect pregnancy

—why in birth control

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17
Q

Stages of menstrual cycle (follicular and leutal 14 14 days)

A

Follicle

Maturing follicle

Ovulation

Corpus luteum

Degenerative C luteum

18
Q

APGAR score

A

Universal new born recessment

5 domains
0,1,2 points with max score of ten

Give at 1-5 min of life and additional 10 is recessive measures

19
Q

APGAR

A

Appearance

Pulse rate

Grimace

Activity respiration

20
Q

Normal score

A

2 on each domain for 10

21
Q

Appearance

A

2 pink everywhere

1 blue skin on extremities and pink on head and trunk (acrocyanosis)

0 points -blue or pale skin throughout body

22
Q

Pulse

A

2 point->100bpm
1 point-detectable pulse; HR<100
0 points-pulseless

23
Q

Grimace

A

2 points crying
1 point-grimacing with stimulation
0 points - no response to stimulation

24
Q

Activity

A

2 point-actively moving, resists extension of limbs
1 point-flexed limbs easily extended without resistance
0-no movement or resistance

25
Q

Respiration

A

2-strong cry
1 -slow or irregular gasping
0- no respiratory effort at all

26
Q

Androgens

A

Predominant sex steroids in men —male physical characteristics

Testosterone, DHT, androstenedione

27
Q

Testosterone

A

middle potent?

From tests from FSH and LH

Internal male genitalia-except prostate
-epididymis, seminal vesicles, vas deferens

Growth of penis, spinal vesicles, sperm

Increase skeletal muscle growth, flight increase RBC, deepening of voice, increase libido

Close epiphyseal plates when converted to estrogen

28
Q

Androstenedione

A

Weak androgenic and estrogenic properties

Synthesized in adrenals

29
Q

Exogenous testosterone

A

Negative feedback on GnRH, FSH, LH

Decrease testosterone

Atrophy of testes

Decrease testosterone in testes despite high serum levels

Azospermia

30
Q

DHT

A

Most potent

Differentiation penis, scrotum, prostate-BHP in older men
Male bald

Increase sebaceous gland

31
Q

How make DHT

A

T->DHT with 5 a reductase

32
Q

3 month milestone

A

Gross motor-start to roll over

Fine motor-can put hands together connect left and right brain

Verbal/cognitive-laughing, squealing

33
Q

6 month

A

Gross motor-sit up unassisted

Verbal cognitive-single syllables

Fine motor-transfer thing from one hand to other

Self care-can self feed, bring food to mouth

34
Q

9 month

A

Gross motor-crawling

Verbal/cognitive-object permanence (if put block behind back know it is there still! Know it is in existence)-peek a boo worthless before

35
Q

12 month

A

Gross motor-stand walk

Verbal cog-1-3 words

Self care-drink from cup

36
Q

15 months

A

Walk backward, run

6 words

2 cube tower

Use fork and spoon

37
Q

18 m

A

Gross motor-climb stairs, kick a ball

Verbal cognitive-combine words

Fine motor-4 cube tower

Social self care-brush teeth with help

38
Q

2 years

A

Gross motor-jump up

Verbal cognitive-half understandable

Fine motor-6 cube tower *

Self care-wash and dry hands

39
Q

3 years

A

Gross motor-jump forward, a tricycle

Verbal cognitive-understandable,

Fine motor-copy a circle or dash

Self care-bowl of cereal, brunch teeth, dress

40
Q

Between 2-3

A

Gender identity

Know output-when potty train

4 year old in pull ups-look at developmental history

41
Q

4 years

A

Gross motor-hop on a foot

Fine motor-copy a plus sign, draw a stick figure

Social self care-button clothes

*magical thinking, superheroes, Disney park, imaginary friends