Reproductive Flashcards
Estradiol
Most abundant sex hormone during reproductive years
Most potent
DIOLing up
Synthesized in ovaries only in reproductive years
Estrone
Synthesized in adipose
Weaker than estradiol
Predominant sex steroid after menopause
Exhausted ovaries looking to fat and saying ON YOUR OWN
Estriol
Pregnancy in massive quantities
Weaker than estradiol or estrone
Preg
All three increase estriol increase most
Estrogen receptor
Cytoplasm into nucleus
LH FHS
Increase estradiol which inhibits with neg feedback except surge
Estrogen effects
Development of female primary and secondary sex characteristics
Stimulate development of genitals, breasts, and follicles in ovaries
Thickening of vaginal wall
Increase vag lubrication
Stimulate growth of uterus and endometrial lining
Increase fat storage in female distribution
Bone estrogen
Close growth plate
Halt linear growth of bones
Girls-shorter bc start puberty earlier
Increase bone formation , decrease resorption why wome get osteoporosis after menopause
Estrogen blood
Increase transport proteins
Increase HDL
Decrease LDL
Why women hav lower CDV risk
Estrogen and progestin
Inhibit ovulation
Hormone replacement therapy
Progesterone
Steroid sex hormone
Produced in corpus luteum, placenta, adrenals and testes
In all hormone contraceptions
Pro-gestation(counteract rejection of foreign body)
Progesterone receptor
In cytoplasm, to nucleus where alter transcription
Effects progesterone
Nourish and protect pregnancy tissue
Progesterone and endometrial lining
Glandular secretionsincrease spiral artery formation (nutrients come in)
Inhibit contractions
Cervix progesterone
Increase production of thick cervical mucus
Protects pregnancy from infections
Prevent sperm to enter uterus (contraception
Progesterone and ER receptors
Decrease ER inc ells to put on hold and protect pregnancy
—why in birth control