Reproductive Flashcards

1
Q

Estradiol

A

Most abundant sex hormone during reproductive years

Most potent

DIOLing up

Synthesized in ovaries only in reproductive years

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2
Q

Estrone

A

Synthesized in adipose

Weaker than estradiol

Predominant sex steroid after menopause

Exhausted ovaries looking to fat and saying ON YOUR OWN

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3
Q

Estriol

A

Pregnancy in massive quantities

Weaker than estradiol or estrone

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4
Q

Preg

A

All three increase estriol increase most

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5
Q

Estrogen receptor

A

Cytoplasm into nucleus

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6
Q

LH FHS

A

Increase estradiol which inhibits with neg feedback except surge

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7
Q

Estrogen effects

A

Development of female primary and secondary sex characteristics

Stimulate development of genitals, breasts, and follicles in ovaries
Thickening of vaginal wall

Increase vag lubrication
Stimulate growth of uterus and endometrial lining
Increase fat storage in female distribution

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8
Q

Bone estrogen

A

Close growth plate

Halt linear growth of bones

Girls-shorter bc start puberty earlier

Increase bone formation , decrease resorption why wome get osteoporosis after menopause

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9
Q

Estrogen blood

A

Increase transport proteins

Increase HDL

Decrease LDL

Why women hav lower CDV risk

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10
Q

Estrogen and progestin

A

Inhibit ovulation

Hormone replacement therapy

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11
Q

Progesterone

A

Steroid sex hormone

Produced in corpus luteum, placenta, adrenals and testes

In all hormone contraceptions

Pro-gestation(counteract rejection of foreign body)

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12
Q

Progesterone receptor

A

In cytoplasm, to nucleus where alter transcription

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13
Q

Effects progesterone

A

Nourish and protect pregnancy tissue

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14
Q

Progesterone and endometrial lining

A

Glandular secretionsincrease spiral artery formation (nutrients come in)

Inhibit contractions

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15
Q

Cervix progesterone

A

Increase production of thick cervical mucus

Protects pregnancy from infections

Prevent sperm to enter uterus (contraception

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16
Q

Progesterone and ER receptors

A

Decrease ER inc ells to put on hold and protect pregnancy

—why in birth control

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17
Q

Stages of menstrual cycle (follicular and leutal 14 14 days)

A

Follicle

Maturing follicle

Ovulation

Corpus luteum

Degenerative C luteum

18
Q

APGAR score

A

Universal new born recessment

5 domains
0,1,2 points with max score of ten

Give at 1-5 min of life and additional 10 is recessive measures

19
Q

APGAR

A

Appearance

Pulse rate

Grimace

Activity respiration

20
Q

Normal score

A

2 on each domain for 10

21
Q

Appearance

A

2 pink everywhere

1 blue skin on extremities and pink on head and trunk (acrocyanosis)

0 points -blue or pale skin throughout body

22
Q

Pulse

A

2 point->100bpm
1 point-detectable pulse; HR<100
0 points-pulseless

23
Q

Grimace

A

2 points crying
1 point-grimacing with stimulation
0 points - no response to stimulation

24
Q

Activity

A

2 point-actively moving, resists extension of limbs
1 point-flexed limbs easily extended without resistance
0-no movement or resistance

25
Respiration
2-strong cry 1 -slow or irregular gasping 0- no respiratory effort at all
26
Androgens
Predominant sex steroids in men —male physical characteristics Testosterone, DHT, androstenedione
27
Testosterone
middle potent? From tests from FSH and LH Internal male genitalia-except prostate -epididymis, seminal vesicles, vas deferens Growth of penis, spinal vesicles, sperm Increase skeletal muscle growth, flight increase RBC, deepening of voice, increase libido Close epiphyseal plates when converted to estrogen
28
Androstenedione
Weak androgenic and estrogenic properties Synthesized in adrenals
29
Exogenous testosterone
Negative feedback on GnRH, FSH, LH Decrease testosterone Atrophy of testes Decrease testosterone in testes despite high serum levels Azospermia
30
DHT
Most potent Differentiation penis, scrotum, prostate-BHP in older men Male bald Increase sebaceous gland
31
How make DHT
T->DHT with 5 a reductase
32
3 month milestone
Gross motor-start to roll over Fine motor-can put hands together connect left and right brain Verbal/cognitive-laughing, squealing
33
6 month
Gross motor-sit up unassisted Verbal cognitive-single syllables Fine motor-transfer thing from one hand to other Self care-can self feed, bring food to mouth
34
9 month
Gross motor-crawling Verbal/cognitive-object permanence (if put block behind back know it is there still! Know it is in existence)-peek a boo worthless before
35
12 month
Gross motor-stand walk Verbal cog-1-3 words Self care-drink from cup
36
15 months
Walk backward, run 6 words 2 cube tower Use fork and spoon
37
18 m
Gross motor-climb stairs, kick a ball Verbal cognitive-combine words Fine motor-4 cube tower Social self care-brush teeth with help
38
2 years
Gross motor-jump up Verbal cognitive-half understandable Fine motor-6 cube tower * Self care-wash and dry hands
39
3 years
Gross motor-jump forward, a tricycle Verbal cognitive-understandable, Fine motor-copy a circle or dash Self care-bowl of cereal, brunch teeth, dress
40
Between 2-3
Gender identity Know output-when potty train 4 year old in pull ups-look at developmental history
41
4 years
Gross motor-hop on a foot Fine motor-copy a plus sign, draw a stick figure Social self care-button clothes *magical thinking, superheroes, Disney park, imaginary friends