Reproduction Flashcards
Cell Cycle Stages
G1, S, G2, M
G-0 Stage
cell is living without any preparation for division
Chromatin
uncondensed form of the chromosome found during interphase
G1 Stage
cells create organelles for energy/protein production, increase in size
Restriction point
The pass between G1 and S stages where the cell must meet certain requirements including proper DNA
S stage
Stage of the cell cycle where the cell duplicates its DNA
Centromere
The region binding the two sister chromatids following DNA replication
G2 Stage
The checking stage of the cell cycle, cell ensures DNA has been replicated properly and there is enough organelles for replication
M Stage
Mitosis, the cell actually divides
p53
The protein responsible for the restriction point that can put the cell in arrest if DNA is not good enough quality
Cyclins
group of proteins responsible for cell cycle regulation, vary in concentrations as the cycle progresses, forming complexes with CDK’s
CDK
Cyclin dependent kinase, form complexes with specific cyclins during cell cycle progression to phosphorylate cycle txn factors
Cancer
Mutations in the proteins of the cell cycle cause uncontrolled cellular proliferation
Tumor
An mass of cancerous cells undergoing unregulated growth
metastasis
Cancerous cells enter the bloodstream and begin to spread throughout the body
Prophase
1st stage of mitosis: chromatin condenses into chromosomes, centrioles move to opposite poles, spindle fibers project to chromosomes as nuclear membrane dissolves
Centrosome
region outside of the nucleus where the centrioles reside
Spindle Fibers
microtubule projections from the centriole that make contact with the chromosomes
Asters
MT’s projecting from the centriole that anchor it to the cell membrane
Kinetochores
Protein complex at the centromere that allow for spindle fiber attachment
Metaphase
Centriole pairs at opposite poles of the cell use spindle fibers to align the chromosomes alongthe middle of the cell
Metaphase plate
The alignment of chromosomes equidistant from the two poles of the cell during metaphase
Anaphase
Centromeres split and the sister chromatids are pulled towards opposite ends of the cell
Telophase
Spindle fibers disappear, nuclear membrane reforms, chromosomes uncoil back to chromatin
Cytokinesis
Seperation of the cytoplasm and organelles creating two new daughter cells
Synapsis
The intertwining of homologous chromosomes during prophase I
Tetrad
The synaptic pair of homologous chromosomes contains four chromatids total so its a tetrad
Chiasma
The point of synapsis
Crossing Over
The exchange of DNA between homologous chromosomes at the point of synapses during Prophase 1 of meiosis
Mendels Second Law of Independent Assortment
The inheritance of one allele has no effect on the likelihood of inheriting certain alleles for other genes
Disjunction
The separation of homologous pairs during anaphase I
Mendel’s First Law of Segregation
The distribution of homologous chromosomes between two daughter cells, whether each cell gets paternal or maternal cells are random