Reproduction Flashcards
What is the cause of hermaphroditism?
Chromosomal abnormalities
- XO/XXX - Ovarian dysgenesis/ hypoplasia/ immature
- XXY - Testicular hypoplasia, torty cats
Mullerian duct
Embryonic uterine horn - the paramesonephric duct in the male
Wolffian duct
Ductus deferens - the mesonephric duct in the female
What is a true hermaphrodite
Possesses both sets of gonads - may be bilateral, unilateral (with an ovotestis structure) or lateral (one ovary, one testis
What is a pseudohermaphrodite?
Gonads of one sex but the external features of the other
Free martinism
Grossly, cause
Due to humoral alteration of the female within a heterosexual twin set sharing placental blood
Leads to hypoplasia of the ovaries and hypoplastic vulva in the female twin
When does intrafollicular haemorrhage occur?
When might traumatic haemorrhage occur in the ovary?
Ovulation
Traumatic corpus luteum rupture (or cysts)
What type of hermaphrodite is shown here?
Unilateral true
What type of hermaphrodite is shown here?
Pseudo
What is shown here?
Ovarian hypoplasia due to free martinism
Intrafollicular haemorrhage secondary to traumatic enucleation of an ovarian cyst
Describe this lesion
Focal enlargement of the ovary with surrounding haemorrhage. The ovary is oozing a creamy white thick exudate (suppuration). Surrounding tissues seem enlarged.
Acute focal moderate to severe suppurative ovaritis
Arcanobacterium pyogenes
Why does chronic ovarian inflammation result in reduced fertility?
Leads to adhesions in the uterine tube - follicle cannot pass through
Paraovarian cysts - sit adjacent to the oviduct
Remnant of the Wolffian ducts
What are the three different types of ovarian cysts which can been found?
- Follicular cysts - undeveloped follicles - may secrete oestrogen (persistent bulling)
- Luteal cysts - lutinised anovulatory follicles - produce progesterone (anoestrus)
- Cystic CL - premature closure of the ovulation site - not clinically significant
Describe this lesion
The ovarian architecture is disrupted by multifocal distinct cystic structures (2x2cm) which are filled with transluscent red-yellow fluid.
Chronic multifocal moderate to severe polycystic ovarian disease
Follicular cysts - likely to lead to persistent bulling in the cow
Cystadenoma
Cystic adenoma
Describe this lesion
Highly invasive, disrupts the entire architecture of the ovary. Multifocally haemorrhagic. Non-encapsulated. Invasive
Ovarian (papillary) cystadenocarcinoma
What types of hormone may be secreted by granulosa cell tumours?
Progesterone
Oestrodiol
Testosterone
Describe this lesion found in a mare with persistent oestrus behaviour
The ovary is diffusely enlarged and on the cut surface it can be seen that the normal architecture is diffusely disrupted by infiltrative cystic structures containing clear exudative type fluid. Cysts range from 0.5-1cm in diameter. An area of focal haemorrhage is seen on the ovarian surface.
Ovarian granulosa cell tumour
Describe this ovarian tumour.
Well differentiated cells, cystic structures filled with amorphous haemorrhagic exudate.
Little pleomorphism and mitosis seen
Describe this lesion
Ovarian architecture is diffusely disrupted by a large (4x4cm) oval mass which is un-encapsulated and well-demarcated. Space occupying.
Histologically cells appear round with large nuclei and lots of mitoses are seen.
Ovarian dysgerminoma
What is a teratoma?
A tumour which arises from multipotential cells that produce tissues from 2 or 3 embryological layers (ectoderm, mesoderm + endoderm).
What is this?
Teratoma!