Reproduction Flashcards

1
Q

Apposition

A

When blastocyst contact the implantation sits on the endometrium

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2
Q

First trimester duration

A

First trimester duration
1-12 weeks (all organs are formed)

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3
Q

Second trimester duration and symptoms

A

13-28 weeks (growth of organs)
Morning sickness
Back & leg pain
Constipation
Cramps
Fetal movements are felt

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4
Q

Third trimester

A

29-40 weeks (fetus is full term & can live outside mother)
Breathlessness due to push of uterus agains the diaphragm
Varicose veins
Urinary incontinence
Difficulty in sleepy

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5
Q

Hormones controlling pregnancy

A

Estrogen
Progesterone
HCG (predominant hormone in 1st trimester)
Human chorionic somatomamotropin

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6
Q

Role of estrogen in pregnancy

A

Enlargement of breast
Enlargement of uterus
Enlargement of external genitalia
Relaxing of pelvic ligaments

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7
Q

Role of HCG in pregnancy

A

Persistence of corpus luteum to prevent menstruation
Stimulate angiogenesis
Stimulate release of progesterone from CL
Inhibit immunity and phagocytosis from mother cells
Relax uterine muscles & prevent contraction

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8
Q

Role of progesterone in pregnancy

A

Dev of decidual cells for nutrition
Decrease uterine contraction to prevent abortion

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9
Q

Hormones controlling birth

A

Oxytocin
Estrogen
Prostaglandins
Cortisol
Relaxin

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10
Q

Role of estrogen & oxytocin in birth

A

Synthesis of prostaglandins

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11
Q

Role of prostaglandins in birth

A

Increase contraction of uterus by increasing calcium in uteruine cells

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12
Q

Role of cortisol in birth

A

Help the mother withstand labor

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13
Q

Role of relaxin in birth

A

Relax pelvic ligaments for easy delivery

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14
Q

Duration of pregnancy

A

40 weeks from LMP
38 weeks from conception

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15
Q

Antagonist of prostaglandins

A

Progesterones ( prevents uterine contraction)

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16
Q

Homologue of HCG

A

Luteinizing hormone

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17
Q

1st trimester complications

A

Miscarriage
Vaginal bleeding
Nausea
Ectopic pregnancy

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18
Q

2nd trimester complications

A

Preterm labor
Gestational diabetes mellitus

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19
Q

3rd trimester complications

A

Hypertension
Separation of placenta before birth

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20
Q

Post-partum complications

A

Hemorrhage due to lack of uterine contraction
Adherent placenta
Remnants of placenta

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21
Q

Viropause

A

A condition in men characterized by emotional and physical changes in the body due to level of androgens caused by aging
Also call male andropause or climacteric

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22
Q

Cryptochidism

A

A condition characterized by lack of descent of testes
Treated with testosterone injections or gonadotropic drugs which initiate decent
Surgery may be needed if inguinal canal is too small

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23
Q

Extirpation of testes

A

Removal of testes at different stages of life
Before puberty, immediately after puberty, in adulthood

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24
Q

Azoospermia

A

Absence of sperm in semen

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25
Q

Oligozoospermia

A

Low sperm count
Cause: use of corticosteroids

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26
Q

Teratozoospermia

A

Presence of morphologically abnormal sperms

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27
Q

Aspermia

A

Absence of semen due to retrograde ejaculation due to dysfunction of the sphincter

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28
Q

Oligospermia

A

Low volume of semen

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29
Q

Hematospermia

A

Presence of blood in semen due to infections

30
Q

Source of estrogen

A

Non pregnant women: theca cells, corpus luteum and adrenal cortex
Pregnant women: placenta

31
Q

Source of progesterone

A

Non pregnant: theca cells and adrenal cortex
Pregnant: corpus luteum and placenta

32
Q

End products of estrogen metabolism

A

B- estradiol
Estriol
Estrone

33
Q

Synthesis estrogen, progesterone and testosterone

A

Cholesterol or acetate

34
Q

Transport of testosterone

A

Sex steroids binding globulin
Albumin

35
Q

Transport of estrogen and progesterone

A

Albumin and globulin

36
Q

Follicular phase of the ovary

A

From 5th day to ovulation
Primordial follicle
Primary follicle
Vesicular follicle
Graafian follicle

37
Q

Luteinization

A

Conversion of granulosa and theca interna cells into lutein cells

38
Q

Luteolysis

A

Degeneration of corpus luteum

39
Q

End products of progesterone metabolism

A

Pregnonediol

40
Q

Postmenopausal syndrome

A

Physical, physiological and psychological changes occurring in a woman immediately after menopause

41
Q

Symptoms of Postmenopausal syndrome

A

Hot flashes, vasomotor instability, emotional outbursts, depression, fatigue,verigo, headache, osteoporosis and artherosclerosis

42
Q

Treatment of Postmenopausal syndrome

A

Administration of estrogen and progesterone and withdrawing them gradually by reduces the amount

43
Q

Endometriosis

A

When a tissue similar to uterine endometrium develops around the uterus, tubes and ovary
Pregnancy cannot occur
It secretes thick mucus which prevents sperms from entry

44
Q

Caused of male infertility

A

Low sperm count
Abnormal sperms
Obstruction of ducts
Others: crytochidism, alcohol, hypothalamic, pituitary disorders

45
Q

Causes of female infertility

A

Anovulation due to hormonal imbalance
Abnormality of ovary (thick capsule) leads to cyst or fibroids
Abnormality of uterus (endometriosis)
Others: renal, liver, hypothalamic, pituitary disorders

46
Q

Eclampsia

A

Condition characterized by severe hypertension, vascular spasm and convulsions muscular contractions
Treated with vasodilators or termination of pregnancy

47
Q

Gestation period

A

Period of pregnancy
40 weeks from LMC
38 weeks from fertilization

48
Q

Braxton Hicks contractions

A

Weak, irregular, short and painless contractions to prepare the uterus for labor contractions
Cervix softens but doesn’t dilate

49
Q

Types of contractions

A

Braxton Hicks cobtractions
False labor contractions
Labor contractions

50
Q

Stages of parturition

A

1- stage of labor contractions
2- stage of expulsion of fetus (1hr duration)
3- stage of expulsion of placenta (10-15mins after)

51
Q

Maternal hormones for parturition

A

C- cortisol
C- catecholamines
R- relaxin
O- oxytocin
P- prostaglandins

52
Q

Fxns of estrogen during parturition

A

Increase force of uterine contractions
Increase numbers of oxytocin receptors
Synthesis of prostaglandins

53
Q

Fxns of oxytocin during parturition

A

Stimulates uterine contractions
Stimulates release of prostaglandins

L

54
Q

Fxns of progesterone during parturition

A

Inhibit uterine contractions
Inhibit prostaglandin synthesis by inhibiting phospholipase A release

55
Q

Fxns of relaxin

A

Softening of cervix and its ligaments for easy dilatation
Increase oxytocin receptors
Suppress activity of progesterone
Dev of mammary glands

56
Q

Fxns of prostaglandins during parturition

A

Increase the force of uterine contractions by increasing calcium ions in the uterus

57
Q

Fxns of catecholamines during parturition

A

Increase force of uterine contractions via alpha adrenegic receptors

58
Q

Fxns of cortisol

A

Increase force of uterine contractions and helps mother withstand stress of labor

59
Q

Bohr effect

A

Increase in partial pressure of carbon dioxide decreases affinity of hemoglobin to oxygen and vice versa

60
Q

Fxns of placenta

A

Nutritive
Excretory
Respiratory
Endocrine

61
Q

Fxn of LH in general

A

On females: stimulates secretion if progesterone from corpus luteum, initiates ovulation
On males: stimulates secretion of testosterone from Leydig cells

62
Q

Fxns of hCG during pregnancy

A

Same fxn as LH
Corpus luteum and leydig cells

63
Q

Fxns of estrogen during pregnancy

A

Enlargement of uterus
Enlargement of Breast
Enlargement of external genitalia
Relaxation of pelvic ligaments

64
Q

Progesterone during pregnancy

A

Inhibits uterine contractions
Stimulates development of decidua
Enlargement of breast

65
Q

HCS fxn in pregnancy

A

Protein, lipid and carbohydrates metabolism

66
Q

Menarche

A

First menstrual blood flow

67
Q

Thelarche

A

First changes in mammary gland immediately before menarche

68
Q

Lactation

A

It is the synthesis, secretion and ejection of milk
Two stages:
Milk secretion: lactogenesis and galactopoiesis
Milk ejection

69
Q

Fertility control

A

Used of methods or devices to prevent pregnancy
Also called family planning or contraception

70
Q

Rhythm method

A

Prevention of pregnancy by avoiding intercourse during the dangerous period

L

71
Q

Methods of determining ovulation

A

Measurement of basal body temperature
Measurement of hormone level in blood
Measurement of hormones excreted by urine
Ultrasound

72
Q

Different methods of medical termination of pregnancy

A

Dilation and curettage
Vacuum aspiration
Administration of prostaglandins