Repro Path additional cards Flashcards
What would you see in the repro tract of a mini schnauzer with PMDS?
normal external genitalia
testes attached to cranial end of uterine horns
have: oviducts, uterus, cervix & anterior vagina
What causes PMDS?
lack of MIS or receptor –> persistent Mullerian ducts
Where is the Wolffian duct derived from?
mesonephric ridge
Where is the Mullerian ducts derived from?
lateral surface of mesonephric ridge
How is the undifferentiated gonad formed?
primordial germ cells migrate from embryonic yolk sack to genital ridge
Mesonephric (Wolffian) ducts give rise to?
epididymis, ductus deferens, & seminal vesicles
The urogenital sinus of males gives rise to?
prostate & bulbourethral glands
Paramesonephric (Mullerian) duct gives rise to?
oviduct, uterus, cervix & ANTERIOR vagina
Urogenital sinus of females gives rise to?
CAUDAL vagina
How is sexual differentiation achieved in the male?
- gene on Y chromosome –> SRY–> testes w/ Sertoli cells
- testes produce MIF –> regresses Mullerian ducts
- Leydig cells –> testosterone –> Wolffian ducts remain
- Testosterone –> DHT –> external genitalia
How is sexual differentiation achieved in the female?
- No Y chromosome–> no MIH–> Wolffian ducts regress
Which type of pseudohermaphrodite is more common?
male w/ male gonadal tissue
What is the best example of chimera in vet med?
Freemartin
female & male calf twins
Pathogenesis of Freemartinism?
- mixing of blood between male & female calf twins
- partial masculinization of female –> sertoli cells –> MIF
- uterus & vagina never connect
- external genitalia is often female
What are the 2 forms of bacterial oophoritis? (RARE)
- pyogenic –> D & C–> ascending infection
2. granulomatous –> M. bovis & B. suis
Which species most commonly gets paraovarian cysts?
mares
Cystic ovarian dz. is most common in what animals? Manifestation?
dairy cows
Anesturs
What is believed to cause Cystic Ovarian Dz?
Lack of a LH surge
Cystic ovarian dz can also be an important source of infertility for _____.
sows
What causes Cystic Ovarian dz in sows?
- multiple large cysts –> 2-3 cm diameter–> progesterone –> irregular cycles
small multiple cysts–> 1 cm –> “grapes” –> estrogen & irregular cycles
When does cystic ovarian dz affect dairy cows?
60 post partum
more frequent in winter months
Most common ovarian neoplasm in the mare & cow?
Granulosa cell tumor
often benign
can be fxnal –> estrogens, androgens or inhibin
Fxnal Granulosa Cell Tumor secreting Inhibin will cause what?
Anestrus in the mare or cow (less frequent)
Fxnal Granulosa Cell Tumor secreting Androgens will cause what?
Stallion-like behavior in the mare
Fxnal Granulosa Cell Tumor secreting Estrogens will cause what?
nymphomania in the mare