Repro Flashcards

1
Q

Progesterone implant - how long before it has to be taken out

A

3 years

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Progesterone implant
- how soon after adminsitration is it effective as sole form of contraception

A

if day 1-5 of cycle - immediate effect
otherwise takes 7 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

UKMEC 4 for prgoesterone implant and progesterone injection?

A

Current breast ca or within last 5 years

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

4 side effects of progesterone injection

A
  1. abnormal bleeding (80%)
  2. Mastalgia - common
  3. Delayed return to fertility - can take 1 year
  4. Weight gain
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

pharmacological tx of stress incontinence?
pharmacologcail tx of urge incontinence

A

stress - duloxetine
urge - mirabegron/oxybutynin/tolteridone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

CYP450 inducers

A

Anticonvulsants
Rifampicin
St Johns Wort

–> remember as women on phenytoin shouldn’t use COCP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

CYP450 inhibitors

A

PPI
Macrolide abx
Quinolones (cirpfloxacin)
Antifungals

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Woman is on COCP
She misses 2 pills in during the first 7 ‘active pill’ period. What do you do

A

Take the missed pill now, even if it means taking 2 pills in one go
- if she has had UPSI sine finishing the last packet, needs emergency contraception

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Woman is on COCP
She misses 2 pills in during the last 7 ‘active pill’ period. What do you do

A

Take the missed pill now even if it means taking 2 pills in one go
- commence the next pill packet without taking a pill free interval

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

POP: how long would be considered a ‘delayed’ administration for most POPs?
What is the exception?

A

3 hours

Cerazette (desogestrel)- 12 hours
drospirenone - 24 hours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

How long is a mirena effective for

A

5 years

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

After administration, how soon is the contraceptive effective for copper coil? for mirena?

A

copper coil - immediately (copper is toxic)
mirena - takes 7 days - use barrier contraception during this period

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Drug causes of infertility in men - name 3

A

Sulfasalazine
Steroids
Cytotoxic drugs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Initial blood test in suspected infertility in a woman

A

Mid luteal phase progesterone (confirms ovulation)
- take on 7 days prior to expected period

FSH and LH on day 2-4 on cycle (useful in irregular menses)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is ‘red degeneration’

A

In a pregnant woman with fibroids, the rapid growth of the fibroid may lead to increased demand for blood supply which cannot be met

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Side effect of GNRH agonists used for fibroids?

A

menopausal symptoms
osteoporosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

3 types of fibroid

A

Subserosal - grow into peritoneal cavity –> pressure sx
Submucosal - grow into uterine cavity –> bleeding, pain, infertility
Intramural - within myometrium –> bleeding, pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Current NHS screening for breast ca?

A

every 3 yrs from 50-70yo

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Current NHS screening for cervical ca

A

25-49yo: every 3 years
50- 64yo: every 5 years

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Physiological changes in breathing and circulation in pregnancy?

A

Breathing - increased tidal volume.
resp rate does NOT change in pregnancy

Circulation:
- increased HR
- lower BP in 1st and 2nd trimester
- bounding pulse
- ejection systolic murmur

21
Q

Antepartum haemorhage immediately after artificial rupture of membranes

  • likey diagnosis?
A

vasa praevia
- foetal vessels running close/crossing the inner cervical os

22
Q

LGV (lymphogranuloma venereum)
Cause?
Typical presentation?

A

Caused - chlamydia

Presentation
1) painless pustule –>ulcer
2) painful inguinal LNs
3) proctocolitis (tenesmus, PR bloody discharge, diarrhoea)

23
Q

Chlamydia - treatment?

A

doxycycline

24
Q

What is a missed miscarriage

A

Fetus has died but remains in the uterus, os closed

25
Q

What is adenomyosis?

A

ectopic endometrial tissue growing in myometrium

26
Q

tender breast lump which varies in size during menstrual cycle

A

breast cyst

27
Q

in which group of breastfeeding women is COCP contraindicated (UKMEC 4)

A

if breastffeeding and <6 weeks post partum

28
Q

in which group of smoking women is COCP contraindicated (uKMEC 4)

A

> 35yo
smoking >15 cigs/day

29
Q

HPV types in cervical cancer?

A

16
18
33

30
Q

What is Ashermans syndrome

A

uterine adhesions causing amenorrhoea
most often post D+C

31
Q

Fat necrosis of the breast tends to occur in…?

A

Obese women with large fatty breasts

32
Q

Pharmacological management of menorrhagia

A

1st: Mirena
2nd: tranexamic acid/NSAIDs/COCP
3rd: norethisterone 15mg TDS from days 5-26 of cycle

33
Q

Definition of anaemia in pregnancy?

A

Hb <110

34
Q

home pregnancy tests become +ve how many days post conception?

A

11 days post

35
Q

home pregnancy tests remain +ve how many days post miscarriage?

A

5 days post miscarriage

36
Q

pharmacological management of hot flushes if HRT is contraindicated

A

SSRIs

37
Q

preferred antithyroid medications in pregnancy

A

PTU In 1st trimester
Carbimazole in 2nd trimester

38
Q

painful genital ulcer + lymphadenopathy

A

Haemophilus ducreyi = chancroid

39
Q

COCP provides level of protection against which cancers?

A

endometrial and ovarian

40
Q

rapidly largening and painful lump on the labia?

A

bartholins cyst

41
Q

when is the anomaly scan done?

A

18-20 weeks

42
Q

pharmacological mx of stress incontinence

A

duloxetine - antimuscarinic effect?

43
Q

Normal physiological changes in pregnancy to:
- WCC
- Albumin
- urea
- creatinine
- ALP
- platelets

A
  • WCC increase
  • albumin decreases (dilutes)
  • urea and creatinine decreases (increased clearance)
  • ALP rises
  • platelets decreases
44
Q

management of menorrhagia?

A

contraception needed:
- IUS –> COCP –> POP

no contraception needed:
- tranexamic acid

45
Q

PAINful genital ulcer + lymphadenopathy
–> cause?

A

haemophilus ducreyi

46
Q

at what BMI is COCP considered UKMEC 3?

A

BMI >35

47
Q

when is smoking considered absolute contraindication to COCP use?

A

> 35yo
+ smoking >15 cigarettes/day

48
Q

time period after UPSI for effective administration of copper IUD

A

5 days
or 5 days after expected ovulation, whichever is later