Repro Flashcards
Progesterone implant - how long before it has to be taken out
3 years
Progesterone implant
- how soon after adminsitration is it effective as sole form of contraception
if day 1-5 of cycle - immediate effect
otherwise takes 7 days
UKMEC 4 for prgoesterone implant and progesterone injection?
Current breast ca or within last 5 years
4 side effects of progesterone injection
- abnormal bleeding (80%)
- Mastalgia - common
- Delayed return to fertility - can take 1 year
- Weight gain
pharmacological tx of stress incontinence?
pharmacologcail tx of urge incontinence
stress - duloxetine
urge - mirabegron/oxybutynin/tolteridone
CYP450 inducers
Anticonvulsants
Rifampicin
St Johns Wort
–> remember as women on phenytoin shouldn’t use COCP
CYP450 inhibitors
PPI
Macrolide abx
Quinolones (cirpfloxacin)
Antifungals
Woman is on COCP
She misses 2 pills in during the first 7 ‘active pill’ period. What do you do
Take the missed pill now, even if it means taking 2 pills in one go
- if she has had UPSI sine finishing the last packet, needs emergency contraception
Woman is on COCP
She misses 2 pills in during the last 7 ‘active pill’ period. What do you do
Take the missed pill now even if it means taking 2 pills in one go
- commence the next pill packet without taking a pill free interval
POP: how long would be considered a ‘delayed’ administration for most POPs?
What is the exception?
3 hours
Cerazette (desogestrel)- 12 hours
drospirenone - 24 hours
How long is a mirena effective for
5 years
After administration, how soon is the contraceptive effective for copper coil? for mirena?
copper coil - immediately (copper is toxic)
mirena - takes 7 days - use barrier contraception during this period
Drug causes of infertility in men - name 3
Sulfasalazine
Steroids
Cytotoxic drugs
Initial blood test in suspected infertility in a woman
Mid luteal phase progesterone (confirms ovulation)
- take on 7 days prior to expected period
FSH and LH on day 2-4 on cycle (useful in irregular menses)
What is ‘red degeneration’
In a pregnant woman with fibroids, the rapid growth of the fibroid may lead to increased demand for blood supply which cannot be met
Side effect of GNRH agonists used for fibroids?
menopausal symptoms
osteoporosis
3 types of fibroid
Subserosal - grow into peritoneal cavity –> pressure sx
Submucosal - grow into uterine cavity –> bleeding, pain, infertility
Intramural - within myometrium –> bleeding, pain
Current NHS screening for breast ca?
every 3 yrs from 50-70yo
Current NHS screening for cervical ca
25-49yo: every 3 years
50- 64yo: every 5 years