REPRO Flashcards
What hormone do follicles secrete?
Oestrogen
What is the role of progesterone?
To prepare the animal for pregnancy (closes cervix, endometrial thickening and secretions, mammary development)
How long is the luteal phase in bitches?
~70 days
How long is anestrus?
3-4 months
When does prolactin start to rise?
25 days into the luteal phase (pregnancy or pseudo)
What is the role of prolactin?
Luteotrophic so supports the corpus luteum and therefore progesterone secretion
How can you terminate an unwanted pregnancy 20 days in?
- prolactin inhibitor (Cabergoline) = best (25 days)
- Prostaglandin (side effects) (20 days)
- Progesterone inhibitor like Aglepristone (Alizin) (can be used at any stage but after 20 days signs of partition so not nice for dog)
How can you terminate an unwanted pregnancy within 2 weeks?
Progesterone inhibitor - Aglepristone (Alizin)
If within 72 hours can give oestrogen (Mesalin(
What happens to a queens dominant follicles if ovulation isn’t induced during oestrus?
They regress and there is no luteal phase (inter-oestrus)
How long until the next follicular wave in queens if no ovulation occurs?
16-21 days typically
How can you detect if a queen hasn’t ovulated?
Progesterone concentrations will remain low and oestrogen would be high (no luteal phase)
what stage are dog oocytes release at?
Primary oocytes but survive for a long time in the uterus
3 methods to determine optimal breeding time in bitches
- Measure hormone changes (Progesterone)
- Vaginoscopy
- Behaviour and vulval swelling
After being ovulated, how long until the primary oocyte can be fertilised?
2-5 days
Pathogen you can screen for for bitches and queens?
Bitches: Canine herpesvirus
Queens: FeLV
No bacterial venereal pathogens in UK
Is vaginal hyperplasia an issue during oestrus?
It may prevent breeding by causing the vagina to protrude from the vestibule
What is the endoscopic appearance of vagina during pro oestrus or oestrus?
Oedematous phase with swollen mucous folds
Appearance of vagina when progesterone is starting to rise (just before ovulation)?
More angulated mucosa = time to breed
When can you radiograph to confirm pregnancy?
After mineralisation at 45 days
How can you confirm the presence of ovaries In bitches?
Stimulate oestrogen production by follicles by giving hCG or GnRH, then measure blood concentrations
How can you confirm the presence of ovaries In queens?
Stimulate LH surge and ovulation by giving hCG or GnRH, then measure blood progesterone concentrations
Describe luteal phase cytology:
Lots of neutrophils and small intermediate cells
Normal age of puberty in dogs?
6-23 months, big variation
Normal age of puberty in queens?
6-10 months, influenced by season and body weight