Replication of Viruses Flashcards

1
Q

Step of viral replication when there is the help of peplomers

A

Attachment/Adsorption

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2
Q

Step of viral replication when the virus enters

A

Penetration

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3
Q

Step of viral replication when there is the disintegration of capsid; exposes genome to polymerase that will replicate it

A

uncoating

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4
Q

What kind of viruses further enter the nucleus for replication?

A

DNA viruses

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5
Q

What kind of viruses is replicated in the cytoplasm only?

A

RNA viruses

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6
Q

Step of viral replication when DNA —> mRNA

A

Early transcription

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7
Q

Step of viral replication when mRNA —> viral proteins

A

Early translation

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8
Q

What kind of viruses exit via disintegration of the host cell?

A

Naked viruses

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9
Q

What kind of viruses exit via budding and acquires envelope from host’s cell membrane

A

Enveloped viruses

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10
Q

Period in which there is no extracellular virus(virion)

A

Latent period

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11
Q

Latent period starts from _________ and ends before release

A

penetration

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12
Q

Period in which there is no complete virus inside/outside the cell

A

Eclipse period

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13
Q

Eclipse period starts from ___________ and ends in assembly

A

uncoating

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14
Q

What enzyme is used to replicate DNA normally?

A

DNA-Dependent DNA Polymerase

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15
Q

What enzyme is used in normal transcription to mRNA

A

DNA-Dependent RNA Polymerase

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16
Q

What enzyme is used in RNA replication from RNA utilized by RNA viruses?

A

RNA-Dependent RNA Polymerase

17
Q

What enzyme is used in RNA-dependent DNA polymerase utilized by retroviruses and Hepatitis VIrus(HBV)

A

Reverse transcriptase

18
Q

Mutants that arise which are defective in their capacity to infect as wild type viruses; mutation or deletion in their genome

A

Defective viruses

19
Q

Acquisition of genes from other viruses

A

Recombination

20
Q

A defective virus regains its ineffective capacity if another virus coinfects the cell

A

Complementation

21
Q

When two different species of virus coinfects the same cell and genes from one are packaged with the other

A

Phenotype mixing

22
Q

When one virus alters the cell’s physiology so that another virus can no longer infect it

A

Interference

23
Q

Viruses with gene segments can exchange gene segments with other viruses

A

Reassortment

24
Q

What virus causes chronic infection and synthesizes its polymerase?

A

HBV

25
Q

May or may not cause increase in virulence

A

Genetic drift

26
Q

It is caused by gene reassortment; only occurs in segmented viruses; exchange of an entire segment; alter antigenicity and immune response

A

Genetic shift

27
Q

During assembly virus B is enclosed in another capsid

A

Phenotypic masking

28
Q

Utilizes viruses as vectors

A

Genetic Engineering and Therapy