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MycoViro > Hepatitis > Flashcards

Hepatitis Flashcards

0
Q

genus of picornaviridae

A

hepatovirus

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1
Q

cause of hepa A

A

picornavirus

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2
Q

itsura ng picornavirus

A

spherical particle w/ ssRNA

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3
Q

does hepa A cause chronic live disease

A

no

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4
Q

hepa A has ____ serotypes ______ genotypes

A

1;7

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5
Q

how to destroy picornavirus

A 
autoclave
boiling
dry heat
UV
formalin
chlorine
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6
Q

percent of hepa A among all hepa

A

40%

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7
Q

percentage of complete recovery

A

99%

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8
Q

serological findings in lab diagnosis for hepa A

A

HAV
anti HAV
IgM anti HAV

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9
Q

what serological finding in hepa A indicates recent infection

A

IgM antiHAV

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10
Q

cause of hepa B

A

hepadnavirus

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11
Q

MOT of hepa A

A

fecal oral route

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12
Q

MOT of hepa B

A

parenterally

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13
Q

____ of hepa B develops chronic liver dis

A

5-10%

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14
Q

morphologic forms of hepa B

A

small spherical
tubular or filamentous
large spherical (Dane particle)

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15
Q

composition of Dane particle Hepa B

A

HBsAg envelop

HBcAg core

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16
Q

phenotypes of HBsAg

A

ayw
adw
ayr
adr

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17
Q

major risk factor for hepa B

A

sexual promiscuity

drug abuse

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18
Q

1st sign of recovery from hepa B

A

renewed appetite

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19
Q

clinical syndromes of Hepa B

A

acute
chronic
primary Hepatocellular carcinoma

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20
Q

pathology of hepa B

A

spotty parenchymal cell degen
diffuse lobular inflammation
disruption of liver cell cords

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21
Q

screening for hepaB

A

agglutination test

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22
Q

confirmatory for hepa B

A

ELISA

PCR

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23
Q

sero of hepa B

A 
HBV
HBsAg
HBeAg
HBcAg
anti HBs
anti HBe
anti HBc
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24
Q

hepa b sero that indicates viral replication

A

HBeAg

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25
Q

hepa B sero that indicates past infection

A

anti HBsAg

anti HBcAg

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26
Q

trisls for hepa B tx

A

interferon
adenine arabinoside
steroids
azathioprine

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27
Q

hepaB immune globulin is given to

A

post exposure prophylaxis of + mother

mucosal xposure

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28
Q

cause of hepaC

A

hepacivirus

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29
Q

hepacivirus is under

A

flaviviridae

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30
Q

major cause of post transfusion hepa

A

hepa C

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31
Q

_____ of HCV patients develop chronic illnesses

A

70-90%

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32
Q

MOT of hepaC

A

parenteral

sexual

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33
Q

____ is not protective

A

anti HCV

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34
Q

form of hepa C that often leads to cirrhosis

A

chronic form

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35
Q

markers of HepaC

A

HCV

antiHCV

36
Q

smallest known human pathogen

A

hepa D

37
Q

itsura ng hepa D

A

HDAg surrounded by HbsAg envelop

38
Q

hepa D infects only those with

A

underlying HBV inf

39
Q

markers of hepa D

A

HDV
anti HDV
HDAg

40
Q

_____ is protective against delta infection

A

hepa B vaccine

41
Q

Mot of hepa F

A

fecal oral

water borne

42
Q

where was hepa F found

A

one experimental monkey

43
Q

genome of hepa F

A

dsDNA

44
Q

only double stranded na ekek

A

reovirus

45
Q

not know ro cause human disease

A

reovirus

46
Q

causes inapparent infections

A

reovirus

47
Q

most important cause of infantile diarrhea

A

rotavirus

48
Q

single +, naked segmented

A

rotavirus

49
Q

MOT of rotavirus

A

fecal oral route

50
Q

incubation period of rotavirus

A

1-3days

51
Q

most frequent pathogen under rotavirus

A

group A

52
Q

viral excretion of rotavirus in stool persists until

A

50 days

53
Q

rotavirus affects the

A

vili of small int

54
Q

rotavirus diarrhea is caused by

A

impaired sodium and glucose absorption

55
Q

host response to rotavirus

A

IgM > IgG and secretory IgA

56
Q

lab diagnosis for rotavirus

A

ELISA
IEM
LPA
PCR

57
Q

single +, naked icosahedral

A

calicivirus

58
Q

star of David appearance

A

calicivirus

59
Q

why star of David

A

bcoz of 5peplomers

60
Q

incubation for calici

A

24-48hrs

61
Q

causes usually nonbloody non,ucoid stool

A

norwalk virus

62
Q

first incidence of norwalk vrus

A

norwalk, ohio

63
Q

lab diagnosis for norwalk virus

A

RT-PCR
ELISA
IEM

64
Q

is there vaccine for norwalk virus

A

none

65
Q

how dies pironaviridae emter

A

oropharynx
intestinal mucosa
upper RT

66
Q

______ are limited to RT

A

rhinovirus

67
Q

infections by picornaviridae are usually

A

asymptomatic

68
Q

prototype of picornaviridae

A

poliovirus

69
Q

receptor recognized by poliovirus are found in

A 
anterior horn cells of spinal cord
dorsal motor ganglia
motor neurons
skel muscle
lymphoid cells
70
Q

MOT of picornaviridae

A

fecal oral

71
Q

outcomes from poliovirus

A

asymptomatic illness
abortive poliomyelitis
nonparalytic
paralytic

72
Q

types of paralytic poliomyelitis

A

paralytic poliomyelitis
bulbar poliomye
postpolio syndrome

73
Q

viruses associated with herpangina

A

coxsackie A

74
Q

viruses assoc with pleurodynia and myocarditis

A

coxsackie B

75
Q

vesicular lesions arecalled

A

herpangina

76
Q

hand foot mouth disease caused by

A

cox A16

77
Q

other term for pleurodynia

A

bornholm disease

devil’s grip

78
Q

acute febrile illness accompanied by headache and signs kf meningeal irritation

A

viral (aseptic) meningitis

79
Q

feevr and rash may occur in px with

A

echo

cox

80
Q

CSF results from polio or enetero shows

A

lymphocytic pleocytosis

81
Q

CSF glucose is normal or slightly low in

A

viral meningitis

82
Q

where is piliovirus isolated

A

phrynx

83
Q

where does poliovirus grow well

A

monkey kidney tissue culture

84
Q

serological finding in poliovirus inf

A

IgM

4-fold increase in Ab titer

85
Q

types of polio vaccine

A

OPV

IPV

86
Q

which vaccine is made from live attenuated poliovirus

A

OPV

87
Q

which vaccine is cheaper and commonly used

A

OPV

MycoViro (9 decks)

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