Reoviridae Flashcards

1
Q

Reo stands for

A

Respiratory Enteric Orphan

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2
Q

Reoviridae general

A

nonenveloped, spherical

composed of 3 concentic layers (outer, middle Inner)

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3
Q

Reoviridae genome

A

segmented, dsRNA

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4
Q

Reoviridae replication takes place in

A

the cytoplasm

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5
Q

Genetic ____ occurs between viruses within a genus or serogroup

A

reassortment

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6
Q

Orbivirus of sheep causes

A

Bluetongue (BTV)
Reportable
also effects cattle, deer, wild ruminants

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7
Q

BTV: primary reservoir and amplifier (animal)

A

Cattle

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8
Q

BTV: transmission

A

biological transmission by Culicoides

transplacental, veneral possible

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9
Q

BTV: serotypes found in the U.S.

A

10, 11, 13, 17

2 is mainly in southeast

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10
Q

BTV: pathogenesis

A

damage to vascular endothelium- intravascular coagulation - necrosis of organs and tissues

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11
Q

BTV: CS of sheep

A

severe febrile disease, profuse salivation, mucopurulent nasal discharge, laminits, abortion, facial edema
*Cyanosis and necrotic ulceration of tongue

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12
Q

BTV: CS in cattle

A

erosions of buccal cavity, hemo and congestion of muzzle, oral ucleration, mucopurulent nasal discharge, ulcers on teats, facial edema, abortion, lameness

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13
Q

BTV: diagnosis

A

CS, virus isolation, immunohisto, PCR, detect Ab- ELISA, necropsy

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14
Q

BTV: control

A

vaccine, pest control

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15
Q

Orbivirus that infects horses causes

A

African horse sickness (AHS)

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16
Q

AHS- transmission

A

mechanically by culicoides

17
Q

AHS- reservoir

A

Zebras

18
Q

AHS- CS

A

profuse nasal serous and froth discharge, sometimes bloody

intralobular pulmonary edema, facial edema, congested conjunctiva, hydropericardium/peritoneum, petechiae intestine

19
Q

AHS: diagnosis

A

CS, necropsy, virus isolation, serology, PCR

20
Q

AHS: control

A

vaccination, vector control, slaughter infected animals

21
Q

One of the major causes of severe viral diarrhea

A

Rotavirus

22
Q

Rotavirus has characteristic ____ apperance

A

Wheel-like

23
Q

Most common Rotavirus serotype to cause diarrhea

A

RVA- group A rotaviruses

24
Q

Rotavirus: transmission

A

Fecal-oral transmission

25
Q

Rotavirus: main cell of viral replication

A

Mature enterocytes of villi of upper small intestine

26
Q

Rotavirus NSP4 (non-structural protein 4) acts as

A

an enterotoxin

27
Q

Rotavirus: CS

A

severe diarrhea of young, pasty, yellow/pale color feces, sometime mucous or blood flecks
anorexia, dehydration, mild fever

28
Q

Rotavirus: diagnosis

A

PAGE- polyacrylamide Gel electrophoresis

ELISA, PCR, etc.

29
Q

Rotavirus: control

A

vaccine

30
Q

Orthoreovirus is also known as__ causing___

A

Avian Reovirus

viral arthritis/tenosynovitis

31
Q

Avian reovirus normally causes leg weakness in __ (type) chickens

A

Broilers

32
Q

AR: transmission

A

Fecal-oral

tranovarial and inhalation

33
Q

AR localizes in the __ joint

A

Hock joint

34
Q

AR: CS

A

swollen, inflamed hock joints, inflamed synovial membrane, ruptured gastrocnemius tendons
stunted growth, atrophy pancreas

35
Q

AR: diagnosis

A

CS, necropsy, virus isolation, ELISA, PCR

36
Q

AR: control

A

vaccines