Reoviridae Flashcards
Reo stands for
Respiratory Enteric Orphan
Reoviridae general
nonenveloped, spherical
composed of 3 concentic layers (outer, middle Inner)
Reoviridae genome
segmented, dsRNA
Reoviridae replication takes place in
the cytoplasm
Genetic ____ occurs between viruses within a genus or serogroup
reassortment
Orbivirus of sheep causes
Bluetongue (BTV)
Reportable
also effects cattle, deer, wild ruminants
BTV: primary reservoir and amplifier (animal)
Cattle
BTV: transmission
biological transmission by Culicoides
transplacental, veneral possible
BTV: serotypes found in the U.S.
10, 11, 13, 17
2 is mainly in southeast
BTV: pathogenesis
damage to vascular endothelium- intravascular coagulation - necrosis of organs and tissues
BTV: CS of sheep
severe febrile disease, profuse salivation, mucopurulent nasal discharge, laminits, abortion, facial edema
*Cyanosis and necrotic ulceration of tongue
BTV: CS in cattle
erosions of buccal cavity, hemo and congestion of muzzle, oral ucleration, mucopurulent nasal discharge, ulcers on teats, facial edema, abortion, lameness
BTV: diagnosis
CS, virus isolation, immunohisto, PCR, detect Ab- ELISA, necropsy
BTV: control
vaccine, pest control
Orbivirus that infects horses causes
African horse sickness (AHS)
AHS- transmission
mechanically by culicoides
AHS- reservoir
Zebras
AHS- CS
profuse nasal serous and froth discharge, sometimes bloody
intralobular pulmonary edema, facial edema, congested conjunctiva, hydropericardium/peritoneum, petechiae intestine
AHS: diagnosis
CS, necropsy, virus isolation, serology, PCR
AHS: control
vaccination, vector control, slaughter infected animals
One of the major causes of severe viral diarrhea
Rotavirus
Rotavirus has characteristic ____ apperance
Wheel-like
Most common Rotavirus serotype to cause diarrhea
RVA- group A rotaviruses
Rotavirus: transmission
Fecal-oral transmission
Rotavirus: main cell of viral replication
Mature enterocytes of villi of upper small intestine
Rotavirus NSP4 (non-structural protein 4) acts as
an enterotoxin
Rotavirus: CS
severe diarrhea of young, pasty, yellow/pale color feces, sometime mucous or blood flecks
anorexia, dehydration, mild fever
Rotavirus: diagnosis
PAGE- polyacrylamide Gel electrophoresis
ELISA, PCR, etc.
Rotavirus: control
vaccine
Orthoreovirus is also known as__ causing___
Avian Reovirus
viral arthritis/tenosynovitis
Avian reovirus normally causes leg weakness in __ (type) chickens
Broilers
AR: transmission
Fecal-oral
tranovarial and inhalation
AR localizes in the __ joint
Hock joint
AR: CS
swollen, inflamed hock joints, inflamed synovial membrane, ruptured gastrocnemius tendons
stunted growth, atrophy pancreas
AR: diagnosis
CS, necropsy, virus isolation, ELISA, PCR
AR: control
vaccines
