Renovascular Disease- MJ Flashcards
Which 2 things are causes of secondary hypertension? Which one is most common?
- Atherosclerotic RAS (MC)
- Fibromuscular dysplasia
Is it more common for renovascular disease (atherosclerotic RAS or Fibromuscular dysplasia) to be the cause of mild-mod elevated BP or in acute, severe, refractory HTN?
Acute, severe, refractory HTN
(< 1% of mild-mod elevated BP)
T/F: Renovascular disease is associated with target organ injury (LVH and renal fibrosis)
True
If a patient has the following, what disease should you consider?
1. HTN developed at young age
2. Severe or resistant
3. Acute rise over stable value
- Serum creatinine rises >30% after ACE/ARB
- Mod-severe HTN in pt with recurrent episodes of flash pulmonary edema
- Stage II HTN onset after age 55
- Mod-severe HTN in pt with diffuse atherosclerosis, unilateral small kidney, or asymmetric renal size (>1.5 cm)
- Abdominal bruit
Renovascular disease
What is the gold standard for diagnosing Renovascular disease? What test is actually performed in practice?
- Gold standard= Renal arteriography
- What you actually do= CT angio
**only test if intervention will be completed if a significant stenotic lesion is found**
Which renovascular disease is most common in people > 45y/o?
Atherosclerotic renal artery stenosis
Etiology of which renovascular disease?
- Reduced blood flow to kidney
- usually involves aortic orifice or proximal main renal artery
Atherosclerotic renal artery stenosis
What are the 3 risk factors for Atherosclerotic renal artery stenosis?
- Hyperlipidemia
- Cigarette smoking
- > 50y/o
What are 2 comorbidities often seen with atherosclerotic renal artery stenosis?
CAD or PAD
Atherosclerotic renal artery stenosis:
Diagnosis: ______ ______ of at least 60-75%
luminal occlusion of at least 60-75%
How do you treat atherosclerotic renal artery stenosis? (4 things)
- tx the HTN
- monitor CKD
- CV secondary prevention (smoking cessation, diet, etc)
- revascularization (angioplasty w/ or w/o stenting or bypass)
Which renovascular disease is MC in Women < 50y/o?
Fibromuscular dysplasia
Etiology of which renovascular disease?
•Noninflammatory, nonatherosclerotic disorder leading to arterial stenosis, occlusion, aneurysm, dissection, and arterial tortuosity – can effect nearly every arterial be
Fibromuscular dysplasia
What is the agiographic classification of fibromuscular dysplasia?
•multifocal (string of beads) vs. focal (circumferential or tubular stenosis)
(sting of beads is top pic, focal is bottom)
Which renovascular disease has the following clinical presentation?
1. HA
2. Pulsatile tinnitus
3. Neck pain
4. Flank or abdominal pain
- HTN
- Cervical or abdominal bruit
- TIA, stroke
Fibromuscular dysplasia