Renal16 Flashcards
1
Q
ADPKD:
-General
A
- “Adult Polycystic Kidney disease”
- Multiple, large, bilateral cysts that ultimately destroy the kidney parenchyma
2
Q
ADPKD:
-Presentation
A
- Flank pain
- Hematuria
- HTN
- Urinary tract infection
- Progressive renal failure
3
Q
ADPKD:
-Genetics
A
- Autosomal Dominant
- mutation in PKD1 or PKD2
4
Q
ADPKD:
-Cause of death
A
Complications of chronic kidney disease or HTN
-caused by HIGH renin production
5
Q
ADPKD:
-Associations
A
- Berry aneurysms
- Mitral valve prolapse
- Benign hepatic cysts
6
Q
ARPKD:
-General
A
- “Infantile Polycystic Kidney disease”
- Infantile presentation in parenchyma
- Significant renal failure in utero can lead to Potter’s syndrome
7
Q
ARPKD:
-Genetics
A
Autosomal Recessive
8
Q
ARPKD:
-Associations
A
Congenital hepatic fibrosis
9
Q
ARPKD:
-Concerns beyond neonatal period
A
- HTN
- Portal HTN
- Progressive renal insufficiency
10
Q
Medullary Cystic Disease.
A
- Inherited disease causing tubulointerstitial fibrosis and progressive renal insufficiency
- Inability to concentrate urine
- Medullary cysts usually not visualized
- Shrunken kidneys on ultrasound
- Poor prognosis
