Renal12 Flashcards
What are the potential severe complications of kidney stones?
- Hydronephrosis
- Pyelonephritis
What is the composition of the 4 types of kideny stones? and the relative frequency?
- Calcium (80%)
- Ammonium Mg++ PO4- (struvite) (15%)
- Uric acid (5%)
- Cystine (1%)
What types are radiopaque on X-ray?
- Calcium
- Ammonium Mg++ PO4-
- Cystine
What do you see on X-ray for Uric acid stones?
NOTHING! (Radiolucent)
*Visible on CT and ultrasound
Calcium precipitates at?
High pH: calcium phosphate
Low pH: calcium oxalate
Ammonium Mg++ PO4- (struvite) preciptates at?
High pH
Uric acid precipitates at?
Low pH
Cystine precipitates at?
Low pH
Calcium oxalate crystals can result from?
- Hypercalcemic conditions
- Ethylene glycol (antifreeze)
- Vitamin C abuse
What is the most common kidney stone presentation?
Calcium Oxalate stone w
-Hypercalcium or Normocalcemia
What is the treatment for recurrent calcium stones?
Thiazides & citrate
What are “struvite” stones caused by?
Infection w/ urease positive bugs that hydrolyze urea to ammonia -> Urine Alkinalization
- Proteus mirabilis
- Staphylococcus
- Kliebsiella
“Struvite” stones associated with what?
Staghorn calculi
-can be nidus for UTIs
How do you treat Uric Acid stones?
Alkalinization of urine
When do you see Uric Acid stones?
- Strong association with hyperuricemia (e.g., gout)
- Diseases w/ HIGH cell turnover (e.g., leukemia)