Renal System- semester 2 Flashcards
antidiuretic hormone
regulates h2o balance by how much h20 is reabsorbed by nephrons
causes less urine produced
affects diameter of blood vessels
vasopressin
constriction of blood vessel
neuroendocrine cells
release hormones, not neurotransmitters
cell bodies in hypothalamus, axons form posterior pituitary
average urine, lowest, highest
1.5l/day
0.4
25
obligatory urine loss
minimal urine production
posterior pituitary
axon terminals from hypothalamus
secretes ADH
extensive network of capillaries
result when total body h20 decreases
decrease V of extracellular fluid
decrease BP
increase [] of blood
baroreceptors
-at normal BP, send AP to medulla oblongata
(lower BP less AP)
-change HR and BV diameter
-connect to hypothalamus to stimulate release ADH
-trigger low BP, ADH released
osmoreceptors
-within hypothalamus
-send more AP to other neurons, plasma osmolarity increases
-then ADH released
-they change V to increase AP
-synapse on neuroendocrine cells
ADH in collecting duct
ADH binds receptor, info is transmitted
principal cells stimulated by ADH have more aquaporin 2 channels at luminal membrane
-vesicles insert more aquaporin channels into luminal membrane, allowing more h20 in collecting duct cells
no ADH in collecting duct
aquaporin 2 channels moved back, and held in vesicles
-no h20 reabsorbed + impermeable to h2o
ADH and BP relationship
low BP triggers, decrease baroreceptors activity release of ADH
-low total body h2o, decreases MAP
-then ADH increases number of aquaporin 2 channels in luminal membrane
behaviour response to low total body h20
thirst
-triggered but osmoreceptors