renal system Flashcards

1
Q

role of the kidneys

A
  • regulation of extracellular fluid volume and blood pressure
  • regulation of osmolarity (290)
  • maintenance of ion balance
  • regulation of acid base balance
  • exertion of metabolic waste products and foreign chemical
    -secretion, metabolism, and exertion of hormones
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2
Q

solutes are filtered from the blood into Bowmans capsule

A

glomerulus

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3
Q

process of filtration

A
  • filtration
  • reabsorption
  • secretion
    -excretion
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4
Q

excretion =

A

filtration - reabsorption + secretion

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5
Q

purpose of these regulation processes?

A

needs of the boy to maintain homeostasis

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6
Q

Ions the kidneys are balancing

A
  • water and sodium
  • potassium
  • calcium
  • H+ and HCO3-
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7
Q

importance of water and sodium

A

maintains ECF and volume
- important for osmolarity

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8
Q

potassium

A

-important for maintain membrane potential of excitable cells
- disruption: arrhythmias, muscle dysfunction

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9
Q

Calcium

A
  • important for muscle contraction
  • bone formation
  • blood clotting
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10
Q

H+ and HCO3-

A

important for maintaining pH

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11
Q

excess fluid volume is exerted by the kidneys known as

A

diuresis

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12
Q

nephron reabsorb solute without

A

reabsorbing water

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13
Q

lost fluid volume cannot be replaced by the kidneys; they can only conserve it. therefore nephrons job is to

A

reabsorb water without the reabsorbing solute

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14
Q

ADH is stimulated by

A

increase in ECF osmolarity or a fall in blood pressure
- posterior pituitar
- controls the collecting duct permeability to water via insertion of aquaporins

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15
Q

ADH acts on the

A

collecting duct

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16
Q

ADH increases

A

BP

17
Q

the total amount of sodium in the body is a primary determinant of

A

ECF

18
Q

how long does it take kidneys to adapt

A

2 to 3 days

19
Q

major hormone that regulates sodium is

A

aldosterone from the adrenal cortex

20
Q

purpose of aldosterone

A

increases sodium reabsorption
- released form adrenal cortex
- works on the cells of the distal connoted tubule and collecting duct
- increase osmolarity of the blood

21
Q

RAAS stands for

A

renin angiotensin aldosteron system

22
Q

renin is a protein enzyme that is

A

synthesized and stored in an inactive form in the juxtaglomerular cells

23
Q

what’s store in the JG cells

A

renin

24
Q

what happens to JG cells when pressure release?

A

release renin

25
Q

where is macula dense?

A

distal convoluted tubule

26
Q

macula dense measures

A

sodium chloride

27
Q

incread of sodium chloride results

A

the release of renin from the macula dense

28
Q

effects of rennin release

A
  • vasoconstriction
  • ADH increase
  • Thirst increase
    -Aldosterone level increase
29
Q

atrial natriuretic peptide ANP

A
  • synthesized by special atrial cells
    -released in response to atrial stretch due to increased blood volume
  • increases salt and water excretion by suppression renin, aldosterone, and ADH hormones
30
Q

brain natriuretic peptide BNP

A
  • synthesized by special myocardial ventricular cells and brain neurons
  • released in response to increased ventricular pressure and stretch
  • used as a biological marker for heart failure
31
Q

when HCO3- is lost from the body, its is the same as if the body

A

gained a H+

32
Q

the kidney eliminate or replenish H+ by

A

altering plasma HCO3+ concentration