renal system Flashcards

(32 cards)

1
Q

role of the kidneys

A
  • regulation of extracellular fluid volume and blood pressure
  • regulation of osmolarity (290)
  • maintenance of ion balance
  • regulation of acid base balance
  • exertion of metabolic waste products and foreign chemical
    -secretion, metabolism, and exertion of hormones
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2
Q

solutes are filtered from the blood into Bowmans capsule

A

glomerulus

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3
Q

process of filtration

A
  • filtration
  • reabsorption
  • secretion
    -excretion
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4
Q

excretion =

A

filtration - reabsorption + secretion

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5
Q

purpose of these regulation processes?

A

needs of the boy to maintain homeostasis

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6
Q

Ions the kidneys are balancing

A
  • water and sodium
  • potassium
  • calcium
  • H+ and HCO3-
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7
Q

importance of water and sodium

A

maintains ECF and volume
- important for osmolarity

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8
Q

potassium

A

-important for maintain membrane potential of excitable cells
- disruption: arrhythmias, muscle dysfunction

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9
Q

Calcium

A
  • important for muscle contraction
  • bone formation
  • blood clotting
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10
Q

H+ and HCO3-

A

important for maintaining pH

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11
Q

excess fluid volume is exerted by the kidneys known as

A

diuresis

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12
Q

nephron reabsorb solute without

A

reabsorbing water

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13
Q

lost fluid volume cannot be replaced by the kidneys; they can only conserve it. therefore nephrons job is to

A

reabsorb water without the reabsorbing solute

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14
Q

ADH is stimulated by

A

increase in ECF osmolarity or a fall in blood pressure
- posterior pituitar
- controls the collecting duct permeability to water via insertion of aquaporins

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15
Q

ADH acts on the

A

collecting duct

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16
Q

ADH increases

17
Q

the total amount of sodium in the body is a primary determinant of

18
Q

how long does it take kidneys to adapt

19
Q

major hormone that regulates sodium is

A

aldosterone from the adrenal cortex

20
Q

purpose of aldosterone

A

increases sodium reabsorption
- released form adrenal cortex
- works on the cells of the distal connoted tubule and collecting duct
- increase osmolarity of the blood

21
Q

RAAS stands for

A

renin angiotensin aldosteron system

22
Q

renin is a protein enzyme that is

A

synthesized and stored in an inactive form in the juxtaglomerular cells

23
Q

what’s store in the JG cells

24
Q

what happens to JG cells when pressure release?

A

release renin

25
where is macula dense?
distal convoluted tubule
26
macula dense measures
sodium chloride
27
incread of sodium chloride results
the release of renin from the macula dense
28
effects of rennin release
- vasoconstriction - ADH increase - Thirst increase -Aldosterone level increase
29
atrial natriuretic peptide ANP
- synthesized by special atrial cells -released in response to atrial stretch due to increased blood volume - increases salt and water excretion by suppression renin, aldosterone, and ADH hormones
30
brain natriuretic peptide BNP
- synthesized by special myocardial ventricular cells and brain neurons - released in response to increased ventricular pressure and stretch - used as a biological marker for heart failure
31
when HCO3- is lost from the body, its is the same as if the body
gained a H+
32
the kidney eliminate or replenish H+ by
altering plasma HCO3+ concentration