Renal Stones Flashcards
What are the different types of renal stones?
Calcium oxalate (most common),
Calcium phosphate,
Struvite,
Uric acid
Cystine
Describe features of calcium oxalate stones
They precipitate at low saturation levels so they are the most common. Risk factors include: Hypercalcaemia and low urine output, Hyperoxaluria.
Describe features of calcium phosphate stones?
Occurs in renal tubular acidosis types 1 and 3. Low urine volume, hyperparathyroidism
Describe features of struvite stones
Stones formed from magnesium, ammonium and phosphate. Occur as a result of urease producing bacteria and therefore associated with chronic infections
Describe features of cystine stones
Associated with homocystinuria which is an inherited defect.
Where are the three most common areas for stones to become inpacted?
Pelviureteric junction (where renal pelvis becomes ureter)
Crossing the pelvic brim
Vesocpureteric junction (where ureter enters bladder)
What are features of urate stones?
Occur because of high purine levels from diet (red meats) or haematological disorders. Not seen on x-rays
What are the signs and symptoms of renal stones?
- Severe, intermittent loin to groin pain,
- Restlessness,
-Haematuria - Nausea and vomiting,
- Secondary infection
What are the general risk factors for renal stones?
Dehydration,
Hypercalciuria, hyperparathyroidism and hypercalcaemia
Cystinuria
High dietary oxalate
Renal tubular acidosis 1 +3
PKD
Gout
ileostomy (loss of bicarbonate which causes acidic urine and uric acid)
Drugs eg, loop diuretics, steroids, theophylline
What diuretics can promote or prevent renal stones?
Loop diuretics - promote
Thiazide diuretics - prevent as they increase DCT calcium reabsorption
What are some differential diagnosis for renal stones?
Pyelonephritis, appendicitis, diverticulitis, ovraian torsion, ectopic pregnancy, ruptured AAA
What are the investigations for renal stones?
- Urine dip
- Bloods - FBC, CRP, UEs, urate and calcium levels
- Imaging: Gold standard is non-contrast CT KUB in first 24 hours
What is the management of renal stones?
- Analgesia: PR diclofenac or IV paracetamol
- Medical expulsion with tamsulosin if stone <5mm
- Lithotripsy if stone is < 2cm
- Ureteroscopy if pregnant and stone is < 2cm
- Complex stones or staghorn calculi then do percutaneous nephrolithotomy
When should you admit a patient with renal stones?
- Obstructive AKI
- Uncontrollable pain
- Evidence of infection
- Large stones > 5mm
- Person requires IV fluids
What is extracorporeal shock wave lithotripsy?
Sonic waves are used to break up the stone which will then pass spontaneously. Used in stones less than 2cm. Contraindicated in pregnancy