Carotid artery disease Flashcards

1
Q

What is carotid artery disease?

A

Atherosclerotic plaques in the common and internal carotid artery

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2
Q

What are the risk factors for carotid artery disease?

A
  • Age > 65y
  • Smoking
  • Hypertension
  • Hypercholestrolaemia
  • Obesity
  • Diabetes mellitus
  • History of cardiovascular disease
  • Family history
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3
Q

What are the clinical features of carotid artery disease?

A
  • Often asymptomatic (especially if unilateral) but can present with: TIA or stroke
  • Can present with a carotid bruit
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4
Q

What are the differential diagnosis for carotid artery disease?

A
  • Carotid dissection
  • Fibromuscular dysplasia (hypertrophy of vessel wall)
  • Vasculitis (can cause carotid stenosis)
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5
Q

What are the investigations for carotid artery disease?

A
  • Urgent non-contrast CT to assess stroke
  • First line is carotid US doppler with confirmed cases getting a CT angiography
  • Bloods: FBC, UEs, clotting, lipid profile, glucose
  • ECG to look for arrhythmia
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6
Q

What is the acute management?

A

Treatment of stroke.
Ischaemic stroke - If <4.5 hours then aspirin and alteplase.

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7
Q

What is the long term management of carotid artery disease

A
  • Antiplatelet therapy (aspirin and clopidogrel)
  • High dose atorvastatin
  • Management of hypertension
  • Smoking cessation
  • Carotid endarterectomy
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8
Q

What is a carotid endarterectomy?

A

Surgery to remove atheroma and associated damaged intima.

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9
Q

What are the complications of a carotid endarterectomy

A
  • Ischaemic stroke,
  • Nerve damage to hypoglossal, glossopharyngeal or vagus nerve
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