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renal > Renal regulation of sodium, potassium, calcium, phosphate and magnesium > Flashcards

Renal regulation of sodium, potassium, calcium, phosphate and magnesium Flashcards

1
Q

Renal regulation of sodium

A

most common extracellular ion
needed to maintain blood pressure/ volume/ fluid balance

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2
Q

Renal regulation of sodium - FILTRATION

A
  • sodium freely filtered through glomerulus
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3
Q

Renal regulation of sodium - REABSORPTION

A

PCT - 70%

  • actively reabsorbed from tubular cells -> bloodstream
  • na+/k+-ATPase pumps on basolateral membrane

loop of henle - 20% by na/k/cl- cotransporter

DCT/CD - 5% influenced by aldosterone

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4
Q

Renal regulation of sodium - SECRETION

A

sodium is not secreted

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5
Q

Renal regulation of sodium - EXCRETION

A

excretion

  • ADH
  • ANP
  • aldosterone
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6
Q

Renal regulation of potassium

A

most common intracellular ion
needed for nerves/ muscles/ maintain RMP

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7
Q

Renal regulation of potassium - FILTRATION

A

potassium freely filtered at glomerulus

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8
Q

Renal regulation of potassium - REABSORPTION

A

PCT - na/k-ATPase

loop of henle - na/k/cl- cotransporter

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9
Q

Renal regulation of potassium - SECRETION

A

potassium secretion occurs in DCT/CD
- regulated by aldosterone which enhances na/k-ATPase activity

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10
Q

Renal regulation of potassium - EXCRETION

A

depends on dietary intake/ aldosterone/ acid-base levels

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11
Q

Renal regulation of calcium - FILTRATION

A

calcium is freely filtered through glomerulus

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12
Q

Renal regulation of calcium - REABSORPTION

A

PCT - 65% - paracellular
loop of henle - 25% - paracellular
DCT - 10%

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13
Q

Renal regulation of calcium - EXCRETION

A

too much calcium is excreted by action of PTH

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14
Q

Renal regulation of phosphate - FILTRATION

A

phosphate is freely filtered through glomerulus

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15
Q

Renal regulation of phosphate - REABSORPTION

A
  • actively reabsorbed in PCT
  • influenced by na/po34- cotransporters
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16
Q

Renal regulation of phosphate - EXCRETION

A

high phosphate = low PTH = more phosphate excretion

low phosphate = high PTH = less phosphate excretion

17
Q

Renal regulation of magnesium - FILTRATON

A

magnesium is freely filtered through glomerulus

18
Q

Renal regulation of magnesium - REABSORPTION

A

PCT - 70%
loop of henle - 20%
DCT - 10%

19
Q

Renal regulation of magnesium - EXCRETION

A
  • diet
  • plasma magnesium levels

renal (15 decks)

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