Acid-base balance. Buffering of hydrogen ions in body fluids – buffer systems. Flashcards
acid-base balance - definition
pH remains in range of 7.36-7.44 for stable internal environment for homeostasis to prevent acidosis/ alkolosis
acids
release H+ into solution
for example - carbonic acid dissociates into h+ and bicarbonate ions
bases
release OH- into solutions
pH
measures concentration of H+ in solution
pH neutral = 7
pH = -log(H+)
buffers - definition
substances that help maintain a stable pH
accepting/ releasing H+ in response to changes in pH
needed to regulate pH in blood
buffers - example 1
bicarbonate buffer system
= primary buffer system in ECF
when blood pH is too low
- H++HCO3- to form H2CO3 to be converted in CO2 to be exhaled into lungs
when blood pH is too high
-H2CO3⇌H++HCO3− so H+ increases acidity
regulated by lungs/ kidney
buffers - example 2
PHOSPHATE BUFFER = needed for pH regulation inside cells/ kidneys
H2PO4−⇌H++HPO42−
buffers - example 3
PROTEIN BUFFER SYSTEM
proteins contain -COOH group and release H+
proteins contain -NH3 group to accept H+