Acid-base balance. Buffering of hydrogen ions in body fluids – buffer systems. Flashcards

2
Q

acid-base balance - definition

A

pH remains in range of 7.36-7.44 for stable internal environment for homeostasis to prevent acidosis/ alkolosis

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3
Q

acids

A

release H+ into solution
for example - carbonic acid dissociates into h+ and bicarbonate ions

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4
Q

bases

A

release OH- into solutions

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5
Q

pH

A

measures concentration of H+ in solution
pH neutral = 7
pH = -log(H+)

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6
Q

buffers - definition

A

substances that help maintain a stable pH
accepting/ releasing H+ in response to changes in pH
needed to regulate pH in blood

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7
Q

buffers - example 1

A

bicarbonate buffer system
= primary buffer system in ECF

when blood pH is too low
- H++HCO3- to form H2CO3 to be converted in CO2 to be exhaled into lungs

when blood pH is too high
-H2​CO3​⇌H++HCO3− so H+ increases acidity

regulated by lungs/ kidney

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8
Q

buffers - example 2

A

PHOSPHATE BUFFER = needed for pH regulation inside cells/ kidneys

H2​PO4−​⇌H++HPO42−​

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9
Q

buffers - example 3

A

PROTEIN BUFFER SYSTEM

proteins contain -COOH group and release H+
proteins contain -NH3 group to accept H+

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