Renal Pathophysiology Flashcards
1
Q
What is the function of the kidneys?
A
- Excrete waste products
- Regulate water and salt balance
- Regulate pH: acid/base balance
- Endocrine function (renin, erythropoietin)
2
Q
What percentage of cardiac output do the kidney’s receive?
A
25%
3
Q
What type of collagen forms the glomerular basement membrane?
A
Type IV collagen
4
Q
How does uremia cause pericarditis?
A
Patients with uremia develop a lot of fibrin –> causes pericarditis –> very sticky fibrin that accumulates between pericardium and surface of the heart –> then you hear a rub –> can only be seen upon autopsy or removal of some pericardium
5
Q
How do we define chronic kidney disease?
A
Persistent reduction in GFR to less than 60 ml/min/1.73m^2
–> These patients also have a very high risk for CVD
