renal/gu/respiratory/multiorgan Flashcards
Fanconi syndrome
Causal agents: Cisplatin, ifosfamide, expired tetracyclines,
tenofovir
Hemorrhagic cystitis
Causal agents: Cyclophosphamide, ifosfamide
Note: Prevent by coadministering with mesna
Interstitial nephritis
Causal agents: Diuretics (Pee), NSAIDs (Pain-free), Penicillins
and cephalosporins, PPIs, rifamPin, and sulfa
drugs
Note: Remember the 5 P’s
Dry cough
Causal agents: ACE inhibitors
Pulmonary fibrosis
Causal agents: Methotrexate, Nitrofurantoin, Carmustine,
Bleomycin, Busulfan, Amiodarone
Note: My Nose Cannot Breathe Bad Air
Antimuscarinic
Causal agents: Atropine, TCAs, H1-blockers, antipsychotics
Disulfi am-like reaction
Causal agents: 1st-generation Sulfonylureas, Procarbazine,
certain Cephalosporins, Griseofulvin,
Metronidazole
Note: Sorry Pals, Can’t Go Mingle
Nephrotoxicity/
ototoxicity
Causal agents: Loop diuretics, Aminoglycosides, cisPlatin,
Vancomycin, amphoTERicin B
Note: Listen And Pee Very TERriBly
Cisplatin toxicity may respond to amifostine