MSK/Skin/Connective Tissue

Question 1

Drug-induced lupus

Answer 1

Causal agents: Methyldopa, Minocycline, Hydralazine,
Isoniazid, Phenytoin, Sulfa drugs, Etanercept,
Procainamide

Note: Lupus Makes My HIPS Extremely Painful

Question 2

Fat redistribution

Answer 2

Causal agents: Protease inhibitors, Glucocorticoids

Note: Fat PiG

Question 3

Gingival hyperplasia

Answer 3

Causal agents: Cyclosporine, Ca2+ channel blockers,
Phenytoin

Note: Can Cause Puffy gums

Question 4

Hyperuricemia (gout)

Answer 4

Causal agents: Pyrazinamide, Thiazides, Furosemide, Niacin,
Cyclosporine

Note: Painful Tophi and Feet Need Care

Question 5

Myopathy

Answer 5

Causal agents: Statins, fibrates, niacin, colchicine, daptomycin,
hydroxychloroquine, interferon-α,
penicillamine, glucocorticoids

Question 6

Osteoporosis

Answer 6

Causal agents: Corticosteroids, depot medroxyprogesterone
acetate, GnRH agonists, aromatase inhibitors,
anticonvulsants, heparin, PPIs

Question 7

Photosensitivity

Answer 7

Causal agents: Sulfonamides, Amiodarone, Tetracyclines, 5-FU

Note: SAT For Photo

Question 8

Rash (Stevens-Johnson

syndrome)

Answer 8

Causal agents: Anti-epileptic drugs (especially lamotrigine),
allopurinol, sulfa drugs, penicillin

Note: Steven Johnson has epileptic allergy to sulfa
drugs and penicillin

Question 9

Teeth discoloration

Answer 9

Causal agents: Tetracyclines

Note: Teethracyclines

Question 10

Tendon and cartilage

damage

Answer 10

Causal agents: Fluoroquinolones