Cardio

Question 1

Coronary vasospasm

Answer 1

Causal agents: Cocaine, Amphetamines, Sumatriptan, Ergot alkaloids (CASE)

Question 2

Cutaneous flus ing

Answer 2

Causal agents: Vancomycin, Adenosine, Niacin, Ca2+ channel blockers, Echinocandins, Nitrates (flushed from
VANCEN [dancing])

Red man syndrome—rate-dependent infusion reaction to vancomycin causing widespread pruritic
erythema. Manage with diphenhydramine, slower infusion rate.

Question 3

Dilated

cardiomyopathy

Answer 3

Causal agents: Anthracyclines (eg, Doxorubicin, Daunorubicin); prevent with Dexrazoxane

Question 4

Torsades de pointes

Answer 4

Causal agents: Agents that prolong QT interval: antiArrhythmics (class IA, III), antiBiotics (eg, macrolides),
anti“C”ychotics (eg, haloperidol), antiDepressants (eg, TCAs), antiEmetics (eg, ondansetron)
(ABCDE)