Renal Function Flashcards

1
Q

Kidney weighs approximately

A

150 g

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2
Q

What is the length of Ureter

A

25 cm long

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3
Q

How many mL of urine will a nerve reflex is initiated

A

150 mL of urine

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4
Q

How long is the Urethra in Female

A

4 cm Long

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5
Q

Urine is actually a _____ of the kidney

A

Fluid biopsy

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6
Q

Basic structural & Functional unit of the Kidney

A

nephron

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7
Q

How many Nephron PER Kidney

A

1 to 1.5 million

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8
Q

Found primarily in the outer renal cortex.
Specialized for regular filtration of blood and the production of urine.
Primarily involved in reabsorption and secretion under normal hydration conditions

A

Cortical Nephrons

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9
Q

Situated closer to the boundary between the renal cortex and medulla
Crucial for concentrating urine by creating a high osmotic gradient in the medulla.
Enable water reabsorption and regulation of body fluid balance, especially during dehydration.

A

Juxtamedullary Nephrons

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10
Q

Order of Urine Formation

A

Glomerulus > PCT > LOH > DCT > CD > Calyx > R U B U

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11
Q

How many % of the total cardiac output does the Kidney receive

A

25%

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12
Q

Total renal Blood Flow

A

1,200 mL/min

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13
Q

Total Renal Plasma Flow

A

600 - 700 mL/min

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14
Q

Non-selective filter of plasma sunstances w/ a MW of <70,000 Da

A

Glomerulus

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15
Q

Non-selective filter of plasma sunstances w/ a MW of <70,000 Da

A

Glomerulus

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16
Q

1st function to be affected in renal disease

A

Tubular Reabsorption

17
Q

It is the Plasma concentration at which the ACTIVE TRANSPORT stops

A

Renal threshold

18
Q

Renal Threshold for GLUCOSE

A

160-180 mg/dL

19
Q

ADH regulates water reabsorption in

A

DCT and CD

20
Q

condition characterized by excessive secretion of antidiuretic hormone (ADH), leading to impaired water excretion and dilutional hyponatremia.

A

SIADH

21
Q

It consist of the JG cells which produce renin

A

Juxtaglomerular apparatus

22
Q

Aldosterone regulates Sodium reabsorption in the

A

DCT

23
Q

2 major function of Tubular secretion

A

Regulation of ACID BASE Balance
Elimination of waste products not filtered by the glomerulus

24
Q

Major site for removal of non filtered substances ( secretion and reabsorption)

A

PCT

25
Q

Blood in RTA

A

Acidic

26
Q

Failure to produce an acid urine due to inability to secrete Hydrogen ions

A

RTA

27
Q

used to evaluate glomerular filtration

A

Clearance test

28
Q

used to evaluate glomerular filtration

A

Clearance test

29
Q

Most common test for Glomerular Filtration

A

Creatinine

30
Q

Obsolete test for Glomerular Filtration

A

Urea

31
Q

Gold standard and Reference method test for Glomerular Filtration

A

Inulin (MW: 5,200 Da)

32
Q

better marker of renal tubular function than GFR

A

Beta2-microglobulin

33
Q

Alternative test for Creatinine

A

Cystatin C

34
Q

used to evaluate tubular reabsorption

A

Concentration test

35
Q

Patient is deprived of fluid for up to 24 hrs

A

Fishberg Test

36
Q

Compares Day and Night Urine in terms of volume & SG

A

Mosenthal test

37
Q

More accurate and preferred than SG determination

A

Osmolality

38
Q

Methods include in Osmolality

A

Freezing point osmometry & Vapor pressure osmometry

39
Q

Most commonly used and reference method test for tubular secretion & renal blood flow

A

p-aminohippuric acid test (PAH)