CAST Flashcards
Excretion of cast is termed as
Cylinduria
cast is primarily formed in
DCT & CD
Colorless and Translucent; SUBDUED LIGHT is required when using BF microscope
HYALINE CAST
Most fragile; Orange-red color, seen in Glomerulonephritis, Strenuous excercise
RBC cast
Muddy or Brown cast, contains hgb from lysed RBCs
Blood cast or Hemoglobin cast
how to differentiate RTE cast from WBC cast
Phase Microscopy and Supravital stain
seen in lOWER UTI clumped of leukocyte, should not be reported as cast
Pseudoleukocyte cast
Significant in Advanced tubular destruction and Tubular damage; use supravital stain
Epithelial (RTE) cast
granules derived from LYSOSOME of RTE cells, disintegrate when cast is retained in the tubule, SANDPAPER APPEARANCE
Granular (Course and Fine) cast
Significance of granular cast: ‘‘Py G S S’’
Pyelonephritis, Glomerulonephritis, Stress, Strenuous excercise
Brittle highly refractile w/ jagged ends, tend to look like paraffin shavings sitting o top of urine
Waxy cast
Indicates destruction widening of the tubular walls, 2-6x wider than ordinary cast
Broad cast
Crystals are reported as
Rare, few, Moderate or Many/ HPF
Abnormal crystals are reported as
Average No./ LPF
Factors that contribute to crystal formation: ‘’ P S T’’
pH
Solute conc.
Temperature
Normal Acid Crystals ‘‘C A U C H A M’’
Calcium oxalate
Amorphous Urates
Uric Acid
Calcium Sulfate
Hippuric Acid
Acid Urates
Monosodium Urates
Normal Alkaline Crystals: ‘‘M A T A C C’’
Magnesium Phosphate
Amorphous Phosphate
Triple Phosphate
Ammonium Biurate
Calcium Phosphate (Apatite)
Calcium Carbonate
Yellow Brown granules, Fluffy orange, Pink sediment
Turns into Ammnium biurate after adding Ammnonium hydroxide
Amorphous Urates
Amorphous Urates is soluble in
Heat (60C) and Alkali
Turn into URIC ACID after adding ACETIC ACID
Amorphous Urates
Acid Urates
Rhombic (diamond) 4 sided FLAT PLATE (whetstone) LEMON SHAPED; Hexagonal forms mistaken as CYSTINE crys.
Uric Acid
Uric acid is Increased in
Lesch-Nyhan syndrome
Chemotherapy
Gout
The most frequently observed urinary crystals
CaOx
Bipyramidal, Enveloped, Octahedron, Emerald cut ‘’ B E C O’’
Dihydrate (Weddellite)