Renal Filtration, Reabsorption and Secretion Flashcards
what is the high volume of ultrafiltrate from glomerulus
bowman capsule
what does the ultrafiltrate include
water
electrolytes
glucoseamino acids
lipids
urea
creatinine
HCO3
what are the mechanisms of reabsorption/secretion through the tubule
active transport
passive osmosis/diffusion
hormone driven activation
what is NFP
net filtration pressure
forces favoring filtration - forces opposing filtration
what are favoring forces of pressure
systemic arterial pressure
hydrostatic pressure in capillary
what are opposing forces of pressure
hydrostatic pressure in Bowman capsule space
oncotic pressure of glomerular capillary blood
what does the proximal convoluted tubule contain
cuboidal cells with brush border
filtrate contains plasma content
the secretion of what helps to maintain blood pH
H+
what percentage of Na+ is resorbed in the proximal convoluted tubule
65%, therefore 65% of H20 as well
what percentage of Bicarb is resorbed in the proximal tubule
90% to maintain acid-base balance
what part of the LOH is permeable to H20
Thin descending LOH
what part of the LOH is permeable to ions
Thin ascending LOH
what part of the LOH has active transport
thick ascending LOH
Na+/K+/Cl- co-transport proteins
what does active transport within the ascending loop increase
NaCl in interstitial space
what cellular proteins allow for water to diffuse
aquaporins
