Renal drugs Flashcards
which class of diuretics would be most useful for
acute pulmonary edema (classically seen in HF)
loop diuretics
which class of diuretics would be most useful for idiopathic hypercalciuria (–> calcium stones)
thiazide to decrease renal ca excretion
not loops (loops loose ca)
which class of diuretics would be most useful for glaucoma?
acetazolamide
mannitol
which class of diuretics would be most useful for mild to moderate CHF with expanded ECV
loop diuretics
which class of diuretics would be most useful in conjunction with loop or thiazide diuretics to retain K?
postassiujm sparing diuretics
which class of diuretics would be most useful for edema associated w/ nephrotic syndrome
loop
which class of diuretics would be most useful for increased ICP?
mannitol!!!
not for its diuretic action but bc of it acts as osmotic load to draw fluid out of brain interstitium
which class of diuretics would be most useful for mild to mod HTN
HCTZ
which class of diuretics would be most useful forhypercalcemia
loop
which class of diuretics would be most useful for attitude sickness
acetazolamide
which class of diuretics would be most useful for
hyperaldosteronism
spironolactone
eplerenone
both are aldosteron antagonist
pt with HF exacerbation needs diuretics but has a sulfa drug allergy. dam what drug should you use now?
loop and thiazides are bot sulfa drugs
EXCEPT
ethacrynic acid (loop)
what in the nephron does Mannitol work?
PCT and Descending limb, loop of henle
what is mannitols MOA
Osmotic diuretic. –> inc tubular fluid osmolarity –> inc urine flow, dec intracranial/intraocular pressure.
combank
it inhibits Na and H20 reabsorption